Antibacterial Activity ofPiqueria trinervia., a Mexican Medicinal Plant Used to Treat Diarrhea

Abstract

Intestinal infectious diseases are among the top 10 causes of mortality in Mexico. Children under 5 years of age and adults over 65 years are the most affected; the incidence is greater in rural and indigenous communities. Traditional remedies based on medicinal plants are commonly used; however, the biological activity of many of them has been poorly studied. Thus, we evaluated the antimicrobial activity of the hexane, dichloromethane, ethyl acetate, and methanol extracts of aerial parts and roots of the Piqueria trinervia Cav. (Asteraceae) plant used to treat diarrhea in Mexico. The extracts were tested in vitro against 11 strains: Escherichia coli, E. coli multidrug resistant (MDR), Salmonella typhi, Shigella boydii, Staphylococcus aureus, Staphylococcus epidermidis, Yersinia enterocolitica, Vibrio cholerae not toxic, Bacillus subtilis, Enterobacter aerogenes, and Enterobacter agglomerans. The hexane extract obtained from the thick roots was active against the 11 strains. The ethyl acetate extract from the thin roots was active against eight of the strains; poor activity was detected in dichloromethane and methanol extracts.

Pharmacological potential of Bidens pilosa L. and determination of bioactive compounds using UHPLC-QqQLIT-MS/MS and GC/MS

“…On the other hand, development of drug resistance is becoming serious issue to fight against the diseases [ 15 ]. For instance, few bacteria have developed resistance against available antimicrobial agents which has resulted in significant public health problems [ 16 , 17 ]. Herbal medicine has emerges as a health aid during the last 56 decades and showed the bio prospecting for new plant derived drugs [ 18 , 19 ].…”

Piqueria trinervia as a source of metabolites against Giardia intestinalis

“…The other peaks are probably piquerol isomers and other compounds, such as those identified by Ruiz-Esparza et al. ( 2007 ).…”

“…The pulverized materials (760 g) was mixed with Millipore quality water for 24 h. Next, the materials was treated with dichloromethane following the procedures outlined by Ruiz-Esparza et al. ( 2007 ). The remaining solutions were designated as red oil (RO), fractions 1 and 2 (F1 and F2).…”

“… 1992 ) and pathogenic bacteria (Ruiz-Esparza et al. 2007 ). Trinervinol has activity against fungi that parasitized plants (Saad et al.…”

Evaluation of antimicrobial potential of Mallotus phillipensis, Kalanchoe integra and Aegle marmelos on pathogenic bacteria

“…2 Over the years, the increase in antibiotic resistance has generated a considerable worldwide public health problem due to successful bacterial adaptation to antibiotics. 3 In addition, it was found that the synthetic antibiotics are not only costly, but also cause some side effects in the treatment of infectious disease. 4 Thus, scientists are forced to search for new antimicrobial substances derived from various natural sources like plants for the treatment of infectious diseases.…”