Antibacterial activity of ethyl acetate and aqueous extracts of Mentha longifolia L. and hydroalcoholic extract of Zataria multiflora Boiss. plants against important human pathogens

Saeidi, Saeide; Hassanpour, Kazem; Ghamgosha, Mehdi; Heiat, Mohammad; Taheri, Ramezan Ali; Mirhosseini, Seyed Ali; Farnoosh, Gholamreza

doi:10.1016/s1995-7645(14)60229-7

Cited by 27 publications

(12 citation statements)

References 17 publications

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“…These results confirmed the presence of substituted flavonoids, amine and hydroxyl groups that are responsible for biological activity of C. absus. Similar observations were also detected in ethyl acetate extracts of Taraxacum officinale, Menthe longifolia [24] and Albizia adianthifolia [25].…”

Section: Ftir Spectroscopy Analysissupporting

confidence: 82%

Investigative evaluation of Cassia absus for antibacterial capacity and biomimetic synthesis of silver nanoparticles

Jehan¹,

Saeed²,

Khan

et al. 2018

IET nanobiotechnol.

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Cassia absus is used for medicinal purposes for a long time all over the world. In this study, the authors report the antimicrobial potential of C. absus extracts obtained with different solvents. The extract(s) obtained with ethyl acetate yielded the best antibacterial effects because of a rich supply of oxalates and alkaloids in it. The same extract was also exploited for reducing Ag + ions (to metallic Ag 0) for the synthesis of nanoparticles. Electron microscopy revealed that the silver nanoparticles were ∼18-25 nm in diameter. The Fourier-transform infrared evaluation pointed towards the fact that flavonoids present in the plant extract were acting as reductants while amino groups were the bound stabilisation agents to the synthesised nanoparticles limiting the diameter to a certain threshold and avoiding aggregation naturally. A comparative antibacterial assay of C. absus versus Ag nanoparticles showed that the nanoparticles as well as organic (ethyl acetate) extract of the plant checked the growth of selected (MDR) superbugs. However, the biosynthesised Ag nanoparticles returned better antibacterial efficacies than ethyl acetate extract.

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Section: Ftir Spectroscopy Analysissupporting

confidence: 82%

Investigative evaluation of Cassia absus for antibacterial capacity and biomimetic synthesis of silver nanoparticles

Jehan¹,

Saeed²,

Khan

et al. 2018

IET nanobiotechnol.

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“…It is also known that the essential oil of Mentha longifolia has a higher antimicrobial effect than its alcoholic extract due to the presence of menthol, menthone, pepogon, isomenthol. Menthol is the most important compound of Mentha longifolia with its antimicrobial effects reported in various studies [29][30][31][32]. Combination therapy increases antimicrobial activity, minimizes antibiotic toxicity, prevents the occurrence of mutations involved in bacterial resistance during treatment, and also leads to a synergistic antimicrobial activity.…”

Section: Discussionmentioning

confidence: 99%

Detection of adeABC efllux pump encoding genes and antimicrobial effect of Mentha longifolia and Menthol on MICs of imipenem and ciprofloxacin in clinical isolates of Acinetobacter baumannii

Mahmoudi

Shokoohizadeh

Fahim

et al. 2020

BMC Complement Med Ther

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Background: Acinetobacter baumannii is an opportunistic pathogen that causes nosocomial infections especially in patients in intensive care units (ICUs). Accordingly, the aim of our study was to detection of adeABC efllux pump encoding genes and antimicrobial effect of the essential oil of Mentha longifolia and Menthol on the minimum inhibitory concentration (MIC) of imipenem and ciprofloxacin in clinical isolates of A. baumannii. Methods: A total of 75 clinical isolates of A. baumannii were collected. The presence of efflux pump genes was detected by polymerase chain reaction (PCR). The minimum inhibitory concentration (MIC) of the essential oil of Mentha longifolia and Menthol and their combined effect with antibiotics were measured by microbroth dilution method and fractional inhibitory concentration (FIC) index. Results: The frequency of adeA, adeB, and adeC genes in clinical isolates of A. baumannii were 86.7, 90.7, and 92%, respectively. When the essential oil of Mentha longifolia was combined with ciprofloxacin and imipenem, MICs decreased 4-and 8-fold, respectively. In the combination of menthol with imipenem, the resistance to imipenem was reduced from 0-to 16-fold in 90% (63/70) of the isolates. Conclusion: The presence of efflux pump genes in more than 90% of A. baumannii isolates indicates its potential role in inducing imipenem-and ciprofloxacin-resistance in this bacterium. Menthol has an antimicrobial effect as an active ingredient in Mentha longifolia. In the future, the combination of medicinal plants with antibiotics can be used as a complement in treating diseases caused by drug-resistant bacteria such as A. baumannii infections.

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“…Antimicrobial activity of Mentha piperita recorded by other workers against Staphylococcus aureus and Escherichia coli with MIC value 3.67 mg/ml and 31.25 mg/ml respectively (Probst et al, 2011). Several studies reported that Mentha longifolia possessed a broad spectrum antimicrobial activity with MIC value for ethyl acetate extract 1.25 mg/ml against Staphylococcus aureus, Klebseilla pneumoniae (Saeidi et al, 2014) and methanolic extract 34.512µg/ml against Escherichia coli (Razavi et al, 2012). Ocimum basilicum showed antimicrobial activity with MIC value 250 µg/ml against Escherichia coli, Staphylococcus aureus (Zel et al, 2005) and chloroform extract 0.312 mg/ml against Escherichia coli (Balamurugan, 2013).…”

Section: Discussionmentioning

confidence: 99%

Synergistic Effects between Mentha Piperita, Mentha Longifolia and Ocimum Basilicum on Different Bacterial Strains

Adham¹

2015

IJC

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The present study aimed to quantitatively evaluate antimicrobial activity of Mentha piperita, Mentha longifolia and Ocimum basilicum from Lamiaceae family, compare between them and to evaluate the type of interaction between them by microbroth dilution method and calculation of fractional inhibitory concentration. Dried leave of Mentha piperita, Mentha longifolia and Ocimum basilicum were extracted using same extraction method and solvent the highest ratio yielded by Mentha longifolia 9% and lowest ratio yielded by Ocimum basilicum 6%. Mentha piperita exhibit the lowest minimum inhibitory concentration value ranged between 1.5-<0.1 mg/ml, followed by Mentha longifolia and Ocimum basilicum ranged between 3-<0.1mg/ml with minimum bactericidal concentration ranged between 6-0.1875. On combination of leave extract Mentha piperita with Mentha longifolia exhibit the lowest minimum inhibitory concentration value ranged between 0.1875-<0.05 mg/ml, while combination of Mentha longifolia with Ocimum basilicum revealed minimum inhibitory concentration ranged between 0.75-<0.05. Among tested bacterial strain Streptococcus mitis showed high sensitivity against all tested leave extract alone and in combination form. The combinations of Mentha piperita, Mentha longifolia and Ocimum basilicum showed synergistic effects against most of bacteria. Mentha longifolia and Ocimum basilicum revealed antagonistic effect against Staphylococcus aureus. As a result three Lamiaceae species showed broad spectrum antimicrobial activity against isolated bacterial strain and their activity in combination form more pronounced than alone.

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Antibacterial activity of ethyl acetate and aqueous extracts of Mentha longifolia L. and hydroalcoholic extract of Zataria multiflora Boiss. plants against important human pathogens

Abstract: In conclusion, it seems that Z. multiflora and M. longifolia extracts could inhibit the growth of all of the mentioned bacteria.

Cited by 27 publications

References 17 publications

Investigative evaluation of Cassia absus for antibacterial capacity and biomimetic synthesis of silver nanoparticles

Investigative evaluation of Cassia absus for antibacterial capacity and biomimetic synthesis of silver nanoparticles

Detection of adeABC efllux pump encoding genes and antimicrobial effect of Mentha longifolia and Menthol on MICs of imipenem and ciprofloxacin in clinical isolates of Acinetobacter baumannii

Synergistic Effects between Mentha Piperita, Mentha Longifolia and Ocimum Basilicum on Different Bacterial Strains

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