Antibacterial activity of aqueous and ethanolic leaf extracts of &lt;i&gt;Peperomia pellucida&lt;/i&gt; (l.) H. B. &amp; K. (piperaceae) on three gram-negative bacteria isolates.

Akinnibosun, H. A.; Akinnibosun, Faith I.; German, B.E

doi:10.4314/swj.v3i4.51825

Cited by 11 publications

(10 citation statements)

References 6 publications

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“…Traditional uses include treatment of abdominal pain, abscesses, acne, boils, colic, fatigue, gout and rheumatic joint pain [6]. Literature data confirms the hypoglycemic, anti-inflammatory and analgesic effects of P. pellucida [7] and equally its antidiabetic [8] properties.…”

Section: Introductionmentioning

confidence: 99%

Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats

Florence

Huguette

Hubert

et al. 2017

BMC Complement Altern Med

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Background Peperomia pellucida (L.) HBK is consumed as vegetable and used in Cameroonian traditional medicine for the management of diseases and for fracture healing. Therefore the aim of this study was to evaluate the effects of the aqueous whole plant extract of Peperomia pellucida on fracture healing in female Wistar rats.MethodsA drill hole injury was created by inserting a drill bit inthe diaphysis of the femur. The aqueous extract of the whole plant of Peperomia pellucida was administered orally at the doses of 100, 200 and 400 mg/kg to adult female Wistar rats. The vehicle (distilled water) was given to the control. Besides these rats, one group of rats without fracture received the extract (400 mg/kg). After 14 days of treatment, the rats were sacrificed under anesthesia and the effects of the extract were evaluated on body weight, the relative weights of organs (femurs, uteri and ovaries) and on hematology. Bone (calcium, phosphorus, alkaline phosphatase) and serum biochemical parameters (calcium, phosphorus, alkaline phosphatase) were also evaluated. Radiological and histological tests were carried out on the femurs. The mineral content of the plant extract was also investigated.ResultsThe extract induced an increase in body weight at high dose and in WBCs count at low doses. Aqueous extract from Peperomia pellucida increased bone calcium at lowest dose but maintained this parameter at normal range at high dose in fractured rat. Alkaline phophatase and phosphorus concentrations reduced significantly (p < 0.01) at the dose of 400 mg/kg as compared to fractured rats. Moreover, radiological tests revealed a dose dependent formation of callus at the level of the fracture gap, confirmed by the formation of a highly dense and compact fibrocartilagenous callus. The mineral content of the plant extract revealed the presence of calcium, phosphorus, magnesium, sodium and potassium.ConclusionThe aqueous extract of P. pellucida accelerates bone healing due partly to the mineral content of the extract. These results confirm its traditional use in the treatment of bone fractures.

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Section: Introductionmentioning

confidence: 99%

Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats

Florence

Huguette

Hubert

et al. 2017

BMC Complement Altern Med

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“…Pseudomonas aeruginosa and Staphylococcus aureus have been previously described elsewhere (Prescott et al, 2005;Akinnibosun et al, 2008aAkinnibosun et al, , 2008b). …”

Section: Description Of Research Bacteria: Escherichia Colimentioning

confidence: 99%

“…10 -1 and 10 -2 dilution of the supernatant were obtained as concentrations at which antibacterial activity was carried out. (Akinnibosun et al, 2009). The bacteria isolates were maintained on nutrient agar slants at 4 0 C.…”

Section: Preparation Of Ethanolic Extractmentioning

confidence: 99%

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of <i>Boerhavia diffusa</i> L.

Akinnibosun¹,

Akinnibosun²,

Ogedegbe³

2010

Science World Journal

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“…However, there is a fear that aluminum may induce Alzheimer's disease and strong carcinogenic properties (Crapper et al, 1973, Malleavialle et al, 1984. On the other hand, there is evidence that the use of extracts from plant species possessing both coagulating and antimicrobial properties are safe for human health (Muyibi &Okuofu, 1995;Okuda et al, 2000;Ali et al,2004;Akinnibosun et al, 2008Akinnibosun et al, & 2009.…”

Section: Introductionmentioning

confidence: 99%

Synergy Between Moringa oleifera Seed Powder And Alum In The Purification of Domestic Water

Dalen¹,

Pam²,

Izang³

et al. 2010

Science World Journal

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Moringa oleifera seeds were analyzed for chemical composition. Phytochemical screening indicates the presence of saponnins (+(+)), flavonoids (+(-))and alkaloids(+(-)).Insrumental analysis showed also the presence of sodium(15.21+0.10ppm),aluminum (12.210.012) potassium (14.210.013ppm) and sulphate (1.720.011 ppm). Similarly, commercial alum was also analyzed and the results showed the presence of sodium (10.470.1500), aluminum (18.170.024ppm), potassium (8.010.012ppm) and sulphate (3.730.010ppm). Jar test trials on raw water samples displayed favourably characteristics at 60% alum to 40% m.oleifera mg/l blend with total coliform count of 30ml -1 and turbidity of 3.2NTU below the WHO maximum permissible limit of 5NTU. Other parameters determined also showed conformity with WHO standards for drinking water. The results indicate that moringa oleifera has a double advantage compared to commercial alum because of the presence of phytochemicals which have been reported to possess antimicrobial properties with potentials for conjunctive use with alum for water purification in rural communities.

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Antibacterial activity of aqueous and ethanolic leaf extracts of <i>Peperomia pellucida</i> (l.) H. B. & K. (piperaceae) on three gram-negative bacteria isolates.

Cited by 11 publications

References 6 publications

Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats

Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of <i>Boerhavia diffusa</i> L.

Synergy Between Moringa oleifera Seed Powder And Alum In The Purification of Domestic Water

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