Antibacterial Activity Evaluation of Psidium guajava L. (Myrtaceae) Crude Extracts Against Selected Bacterial Pathogens

Saleh, Basel; Al-Mariri, Ayman

doi:10.52763/pjsir.biol.sci.63.2.2020.119.126

Cited by 5 publications

(5 citation statements)

References 4 publications

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“…The microdilution broth susceptibility test was performed according to Saleh and Al-Mariri [ 41 ]. In 96-well microtiter plates, three replicates of five dilutions of extracts (0.5, 1.25, 2.5, 3.75 and 5 mg.mL −1 ) and an antibacterial (ampicillin) in LB broth were prepared.…”

Section: Methodsmentioning

confidence: 99%

Isolation and Identification of Lichen Photobionts Collected from Different Environments in North of Portugal and Evaluation of Bioactivities of Their Extracts

Loureiro,

Morais,

Silva

et al. 2024

Foods

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Lichens are organisms constituted by a symbiotic relationship between a fungus (mycobiont) and a photoautotrophic partner (photobiont). Lichens produce several bioactive compounds; however, the biotechnological exploitation of this organism is hampered by its slow growth. To start studying the possibility of exploiting lichens as alternative sources of bioactive compounds, eighteen lichens were collected in the north of Portugal in order to isolate and study the bioactivity of their photobionts. It was possible to isolate and cultivate only eight photobionts. Three of them, LFR1, LFA2 and LCF3, belong to the Coelastrella genus, the other two (LFA1 and LCF1) belong to the Chlorella genus and for the remaining three photobionts, LFS1, LCA1 and LCR1, it was impossible to isolate their microalgae. These only grow in consortium with bacteria and/or cyanobacteria. All extracts showed antioxidant activity, mainly at a concentration of 10 mg.mL−1. LFS1, a consortium extract, showed the highest antioxidant power, as well as the highest concentration of phenolic compounds (5.16 ± 0.53 mg of gallic acid equivalents (GAE).g−1). The extracts under study did not show significant antibacterial activity against Escherichia coli, Listeria or Salmonella. The Coelastrella sp. and LFA1 extracts showed the highest hyaluronidase inhibition. The LFR1 extract at a concentration of 5 mg.mL−1 showed the highest anti-inflammatory activity (79.77 ± 7.66%). The extracts of Coelastrella sp. and LFA1 also showed greater antidiabetic activity, demonstrating the high inhibitory power of α-amylase and α-glucosidase. LFR1 at a concentration of 5 mg.mL−1, due to its selective cytotoxicity inhibiting the growth of cancer cells (Caco-2 cells), is a promising anticancer agent.

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Section: Methodsmentioning

confidence: 99%

Isolation and Identification of Lichen Photobionts Collected from Different Environments in North of Portugal and Evaluation of Bioactivities of Their Extracts

Loureiro,

Morais,

Silva

et al. 2024

Foods

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“…The inhibitory effects of Ulva lactuca (Chlorophyta), Dilophus spiralis (Phaeophyta), and Jania Rubens (Rhodophyta) against gram-positive and gram-negative bacteria were examined by Saleh and Al-Mariri 34 . It was hypothesized that Phaeophyta extracts were more effective against tested isolates than Chlorophyta and Rhodophyta because they contained more phenolic compounds.…”

Section: Determination Of Antibacterial Activitymentioning

confidence: 99%

Antibacterial Potential of Marine Brown Algae Turbinaria Conoides Against Bacteria Associated with Diabetic Foot Ulcer

Suresh¹,

Poonguzhali²,

Anuradha³

et al. 2023

Int J Life Sci Pharm Res

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The marine brown algae Turbinaria conoides was extracted with different solvents, viz., acetone, ethanol, methanol and distilled water. The extracts were screened for the presence of various phytochemicals and examined for antibacterial activity by agar well diffusion method. Diabetic foot ulcer (DFU) associated bacteria and their respective standard strains, such as Staphylococcus aureus ATCC 5923, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 700603 and Enterococcus faecal ATCC 25922 were used as test bacteria. Among the different solvent extracts, the aqueous extract possessed the maximum zone of inhibition against both test and standard bacterial strains. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of the aqueous extract against test pathogens were 128-4μg. The eluent mixture for separating the active fraction was selected by thin layer chromatography (TLC), which was found to be n-hexane: ethylacetate (6:4) with a maximum of four spots. In column chromatography, 25th -27th-minute fractions showed maximum antibacterial activity against all the DFU bacterial strains. Our study aims to find the use of T. conoides for treating DFU-associated bacterial infections. The objectives include exploring different solvent extracts of T. conoides for antibacterial activity and characterization of bioactive metabolite.

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“…Berdasarkan studi literatur yang telah dilakukan, data aktivitas antibakteri dari ekstrak daun jambu biji dari berbagai literatur dirangkum pada Tabel 1. [26].…”

Section: Hasil Dan Pembahasanunclassified

Potensi Ekstrak Daun Jambu Biji (Psidium guajava) terhadap Penghambatan Staphylococcus aureus Penyebab Ketombe sebagai Bahan Aktif Sampo

Purnawan¹

2023

WSNF

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Ketombe merupakan pengelupasan kulit kepala secara berlebihan, berbentuk seperti sisik-sisik disertai dengan adanya kotoran berlemak, rambut rontok, serta rasa gatal. Masalah ketombe dipicu salah satunya oleh keberadaan bakteri Staphylococcus aureus. Salah satu bagian tanaman yang memiliki aktivitas penghambat bakteri penyebab ketombe adalah daun jambu biji (Psidium guajava) yang mengandung senyawa tanin, triterpenoid, saponin, dan flavonoid sebagai antibakteri. Penulisan ini bertujuan mengetahui potensi dari ekstrak daun jambu biji dalam menghambat bakteri penyebab ketombe, khususnya Staphylococcus aureus berdasarkan kajian beberapa literatur untuk dapat dimanfaatkan sebagai bahan aktif formulasi sampo antiketombe dari bahan alami yang aman digunakan. Metode penulisan dilakukan dalam bentuk kajian literatur (literature review) menggunakan penelusuran jurnal secara online dari platform Google Scholar dan PubMed dengan berbagai kata kunci serta dari literatur ilmiah lainnya yang dipublikasi dalam rentang 5 tahun terakhir. Berdasarkan kajian literatur yang telah dilakukan, ekstrak daun jambu biji banyak mengandung senyawa bioaktif yang berperan dalam menghambat bakteri penyebab ketombe, termasuk salah satunya Staphylococcus aureus serta pengujian menunjukkan aktivitas antibakteri yang dapat dilihat dari pembentukan zona hambat, yakni daerah jernih di sekitar sumuran dengan ekstrak daun jambu biji yang diteliti. Oleh karena itu, ekstrak daun jambu biji berpotensi dimanfaatkan sebagai bahan aktif formulasi sampo antiketombe.

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Antibacterial Activity Evaluation of Psidium guajava L. (Myrtaceae) Crude Extracts Against Selected Bacterial Pathogens

Cited by 5 publications

References 4 publications

Isolation and Identification of Lichen Photobionts Collected from Different Environments in North of Portugal and Evaluation of Bioactivities of Their Extracts

Isolation and Identification of Lichen Photobionts Collected from Different Environments in North of Portugal and Evaluation of Bioactivities of Their Extracts

Antibacterial Potential of Marine Brown Algae Turbinaria Conoides Against Bacteria Associated with Diabetic Foot Ulcer

Potensi Ekstrak Daun Jambu Biji (Psidium guajava) terhadap Penghambatan Staphylococcus aureus Penyebab Ketombe sebagai Bahan Aktif Sampo

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