Antibacterial Activity and Iron Release of Organic-Inorganic Hybrid Biomaterials Synthesized via the Sol-Gel Route

Catauro, Michelina; D’Errico, Ylenia; D’Angelo, Antonio; Clarke, Ronald J.; Blanco, Ignazio

doi:10.3390/app11199311

Cited by 13 publications

(10 citation statements)

References 33 publications

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“…In stark contrast, the SA–DA/Fe 2+ -coated HAP sample possesses the smallest bacterial coverage percentage (less than 5‰), and the live/dead bacteria ratio sharply decreases to 5.8:1. This is because Fe 2+ has a certain bacteria-killing effect, , as shown in Figure S8, endowing the SA–DA/Fe 2+ coating with the best antibacterial performance. The amount of released ferrous iron from SA–DA/Fe 2+ after 1 d immersion in artificial saliva was barely 0.0744 μg/mL according to the ICP-MS data.…”

Section: Resultsmentioning

confidence: 98%

Efficient Antimicrobial Effect of Alginate–Catechol/Fe²⁺ Coating on Hydroxyapatite toward Oral Care Application

Hong

et al. 2022

ACS Appl. Bio Mater.

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Reducing the formation of oral bacterial biofilms is critical to prevent common dental diseases. Though many strategies for restricting bacterial adhesion on tooth surfaces have been reported, a simple method for efficient oral bacteriostasis is still highly expected. Herein, we have proved a soft gel made of an alginate−catechol conjugate (SA−DA) and the ferrous cation (Fe 2+ ) as an effective antibacterial coating on hydroxyapatite (HAP, a tooth model). As suggested by quartz crystal microbalance (QCM) measurements, SA−DA/Fe 2+ coating possessed a high binding affinity to HAP without destruction by either immersion in artificial saliva or simulated tooth brushing. Significantly less protein (bovine serum albumin) and Streptococcus mutans (S. mutans, an oral bacterial model) could be found on HAP after coating with SA−DA/Fe 2+ , indicating that the prepared gel could resist well the adhesion of biofouling and microbes due to its hydrophilicity. Notably, such an antibacterial effect (around 70% S. mutans was inhibited) could be maintained for 3 d, which resulted from the extremely good stability of SA−DA/Fe 2+ coating, as confirmed by QCM analysis. Our results may offer possibilities for developing applications in order to further improve oral hygiene.

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Section: Resultsmentioning

confidence: 98%

Efficient Antimicrobial Effect of Alginate–Catechol/Fe²⁺ Coating on Hydroxyapatite toward Oral Care Application

Hong

et al. 2022

ACS Appl. Bio Mater.

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“…As also reported in [22], the powders were directly placed in the middle of Petri dishes after bacteria plating. The E. coli plates were incubated at 44 • C for 24 h while those of E. faecalis and P. aeruginosa at 36 • C for 48 h. Finally, S. aureus plates were incubated at 36 • C for 24 h. The diameter of inhibition zones (IDs) in relation to Petri dish diameter (PPD) (6 cm) were calculated.…”

Section: Antibacterial Activitymentioning

confidence: 99%

A New System of Sustainable Silico-Aluminous and Silicate Materials for Cultivation Purpose within Sustainable Buildings: Chemical-Physical, Antibacterial and Cytotoxicity Properties

et al. 2022

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In this study, we compared the chemical-physical, antibacterial, and cytotoxicity properties of silico-aluminous and silicate materials for outdoor (green roof, planted walls) and indoor (urban farms, indoor microgreen gardens) cultivation purpose in a context of sustainable construction. Glasses and lightweight aggregates were tailored starting from waste, by-product, and post-consumer and bioproducts (packaging glass cullet, cattle bone flour ash, vegetable biomass ash, spent coffee ground, degreased from biomass of prepupae of Black Soldier Flies) mixed together with a national ferruginous red clay, quarry scrap pumice and, if necessary, with K2CO3 of reagent grade. The first type of material was obtained by melting at 1200 °C and the second one by powder sintering at 1000 °C. All specimens, subjected to antibacterial test, showed both low zone of inhibitions towards two Gram-negative and two Gram-positive bacterial strains. A cytotoxicity test on mouse embryonic fibroblast NIH-3T3 cell line directly exposed to the investigated materials was performed at three different exposure times (1 h, 3 h, and 6 h). Data acquired highlighted that the materials positively affected redox mitochondrial activity of the fibroblast cells. The concentrations of leachate heavy metals detected on selected materials in water at room temperature after 24 h were lower than the European law limit and an interesting release of P, K, and N nutrients was noted for those formulations designed for agronomic purposes. pH, falling on average within the 6.5–7.5 range, is optimal for most crops, and the specific conductivity <2 dS/m indicates no depression danger for crops. Both bulk density <1200 kg/m3 and porosity over 50% seem to ensure good performance of lightening, drainage, water reservation, and oxygenation of the roots.

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“…To evaluate the antibacterial properties of the material, a Kirby-Bauer test was performed as it was recently made for glass hybrid materials [40,41]. Gram-negative bacteria (−), namely Escherichia coli (ATCC 25,922) and Pseudomonas aeruginosa (ATCC27853), and gram-positive bacteria ( +), as Staphylococcus aureus (ATCC 25,923) and Enterococcus faecalis (ATTC29212), were growth in the absence and presence of the sample.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Thermal behavior and antibacterial studies of a carbonate Mg–Al-based layered double hydroxide (LDH) for in vivo uses

Cardinale

Ciprioti

Fortunato

et al. 2022

J Therm Anal Calorim

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The goal of this work is to study the thermal behavior and the antibacterial properties of a MgAl-CO3 layered double hydroxide (LDH), which demonstrated high efficiency in removing chromium (VI) from contaminated industrial wastewater. The compound has been synthesized via co-precipitation route (direct method) followed by hydrothermal treatment, obtaining nanoscopic crystallites with a partially disordered (turbostratic) structure. After its synthesis, the compound was characterized by means of X-ray powder diffraction, field emission scanning electron microscope, inductively coupled plasma atomic emission spectroscopy and analysis and Fourier transform infrared spectroscopy. On the other hand, with the view to check the drug delivery and surgical tools usage of MgAl-CO3, antibacterial tests, performed according to the Kirby–Bauer method, revealed the inability the growth of the pathogenic bacterial strains. Thermogravimetry and differential thermal analysis revealed that evolution of water from the material occurs in two stages upon heating and a noticeable interaction takes place between water (in the vapor phase) and MgAl-CO3. Kinetic analysis of both steps provides almost constant values of activation energy, with the following average values in the range 0.1 < a < 0.9: E1 = (66 ± 9) kJ mol‒1; E2 = (106 ± 7) kJ mol‒1. Finally, prediction of reasonable reaction times extrapolated at 25 and 37 °C has been made from kinetic parameters of the first step, while almost unrealistic reaction time values were determined using the same procedure with kinetic parameters related to the second step.

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Antibacterial Activity and Iron Release of Organic-Inorganic Hybrid Biomaterials Synthesized via the Sol-Gel Route

Cited by 13 publications

References 33 publications

Efficient Antimicrobial Effect of Alginate–Catechol/Fe²⁺ Coating on Hydroxyapatite toward Oral Care Application

Efficient Antimicrobial Effect of Alginate–Catechol/Fe²⁺ Coating on Hydroxyapatite toward Oral Care Application

A New System of Sustainable Silico-Aluminous and Silicate Materials for Cultivation Purpose within Sustainable Buildings: Chemical-Physical, Antibacterial and Cytotoxicity Properties

Thermal behavior and antibacterial studies of a carbonate Mg–Al-based layered double hydroxide (LDH) for in vivo uses

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Antibacterial Activity and Iron Release of Organic-Inorganic Hybrid Biomaterials Synthesized via the Sol-Gel Route

Cited by 13 publications

References 33 publications

Efficient Antimicrobial Effect of Alginate–Catechol/Fe2+ Coating on Hydroxyapatite toward Oral Care Application

Efficient Antimicrobial Effect of Alginate–Catechol/Fe2+ Coating on Hydroxyapatite toward Oral Care Application

A New System of Sustainable Silico-Aluminous and Silicate Materials for Cultivation Purpose within Sustainable Buildings: Chemical-Physical, Antibacterial and Cytotoxicity Properties

Thermal behavior and antibacterial studies of a carbonate Mg–Al-based layered double hydroxide (LDH) for in vivo uses

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Product

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Efficient Antimicrobial Effect of Alginate–Catechol/Fe²⁺ Coating on Hydroxyapatite toward Oral Care Application

Efficient Antimicrobial Effect of Alginate–Catechol/Fe²⁺ Coating on Hydroxyapatite toward Oral Care Application