Anti-urolithiatic activity of Solanum nigrum hydroalcoholic extract in ethylene glycol-induced urolithiasis in rats

Salama, Abeer; El-Kassaby, Mahitab; Hassan, Azza

doi:10.4103/epj.epj_21_19

Cited by 5 publications

(2 citation statements)

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“…Phytochemicals like Tyrosol, Pyrogallol, saponins and Flavonoids extracted from Clitoria ternatea are responsible for antilithiatic activity of the plant. Treatment of hydroalcoholic extract of Clitoria ternatea in rats possibly prevents calcium oxalate crystal deposition in the kidney by preventing hyperoxaluria induced peroxidative damage to the renal tubular membrane surface (22). Again, investigations on T. terrestris treated hyperoxaluria induced male wistar rats exhibited significantly decreased excretion of oxalate, calcium, and phosphate and reduced levels of blood urea nitrogen, uric acid and creatinine in serum.…”

Section: Resultsmentioning

confidence: 93%

A Survey of Ethnomedicinal Plants used for Urinary Tract Infection (UTI) and Kidney Stone in the Nalbari, Sonitpur and Tinsukia Districts of Assam, India

Ali,

Khanikar,

Kataki

2023

IJAM

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Natural products derived from plants have essential biological parts in contradiction of many pathogenic organisms and are considered a principal source of modern synthetic drugs. A thorough field survey of ethnomedicinal plants was conducted between the months of July, 2022 to December, 2022 in three districts of Assam, namely Nalbari, Sonitpur and Tinsukia. Indigenous knowledge of the traditional medicines used for Urinary Tract Infection (UTI), Urinary Tract stones or kidney stones were gathered based on personal interviews and questionnaires. Medicinal plants with their family, local names, parts used and target diseases were documented. A total of 51 species were documented; of which, amaranthaceae family showed the highest number of species (6), followed by malvaceae (4), fabaceae (3), euphorbiaceae (3), asteraceae (3) etc. This survey revealed several effective medicinal plants that have significant pharmacogenetic properties, especially for UTI and kidney diseases.

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Section: Resultsmentioning

confidence: 93%

A Survey of Ethnomedicinal Plants used for Urinary Tract Infection (UTI) and Kidney Stone in the Nalbari, Sonitpur and Tinsukia Districts of Assam, India

Ali,

Khanikar,

Kataki

2023

IJAM

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“…Adult male albino rats of the wistar strain were given doses of Solanum nigrum extract (200 and 400 mg/kg) in the curative group. The effects of ethylene glycol on all biochemical markers and histopathological changes were reversed by treatment with dosages of Solanum nigrum extract 31 .…”

Section: Solanum Nigrummentioning

confidence: 95%

An Overview on Pashanabedha Medicinal Plants

Sunitha,

Narayanaswamy,

Akila

2023

JOPCR

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One of the major kidney diseases that needs a well-targeted therapeutic approach is urolithiasis. For the treatment of lithiasis, a number of medications are available, including diuretics and stone inhibitors, however clinical examination of these medications has revealed a frequency of relapses, adverse effects, and drug interactions. This has served as the justification for the development of new antilithiatic medications, and the hunt for novel molecules has now included herbal medications that provide superior defence and lower relapse rates. Plant-based medications are becoming more popular and are being researched for a variety of illnesses, including lithiasis. A set of medicinal plants known as pashanabheda (literally, ”stonesolving”) are utilised by Ayurvedic doctors in India as anti-urolithiatic medications. The present article reviews the antilithiatic activity of some of the medicinal plants. Here attempt is made to review a few medicinal plants with documented anti-urolithiatic action. In this study, some of the significant plants noted for their antilithiatic effects have been highlighted. Keywords: Urolithiatic; AntiUrolithiatic; Maceration; Turbidimetry; Calcium Oxalate

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Ethnomedicinal study of medicinal plants used by Mizo tribes in Champhai district of Mizoram, India

Laldingliani

Thangjam

Zomuanawma

et al. 2022

J Ethnobiology Ethnomedicine

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Background Medicinal plants have been used countless times for curing diseases mainly in developing countries. They are easily available with little to no side effects when compared to modern medicine. This manuscript encompasses information on ethnomedicinal plants in Champhai district, located in the North East Region (NER) of India. The region lies within Indo-Burma biodiversity hotspot. This study will be the first quantitative report on the ethnomedicinal plants used by the local tribes of this region. Knowledge of medicinal plants is mostly acquired by word of mouth, and the knowledge is dying among the local youths with the prevalence of modern medicine. Hence, there is urgency in deciphering and recording such information. Methods Information was gathered through interviews with 200 informants across 15 villages of the Champhai district. From the data obtained, we evaluate indices such as used report (UR), frequency of citation (FC), informant consensus factor (Fic), cultural values (CVs) and relative importance (RI) for all the plant species. Secondary data were obtained from scientific databases such as Pubmed, Sci Finder and Science Direct. The scientific name of the plants was matched and arranged in consultation with the working list of all plant species (http://www.theplantlist.org). Results Totally, 93 plant species from 53 families and 85 genera were recorded. The most common families are Euphorbiaceae and Asteraceae with six and five species representatives, respectively. Leaves were the most frequently used part of a plant and were usually used in the form of decoction. Curcuma longa has the most cultural value (27.28 CVs) with the highest used report (136 FC), and the highest RI value was Phyllanthus emblica. The main illness categories as per Frequency of citation were muscle/bone problem (0.962 Fic), gastro-intestinal disease (0.956 Fic) and skin care (0.953 Fic). Conclusion The people of Mizoram living in the Champhai district have an immense knowledge of ethnomedicinal plants. There were no side effects recorded for consuming ethnomedicinal plants. We observed that there is a scope of scientific validation of 10 plant species for their pharmacological activity and 13 species for the phytochemical characterisation or isolation of the phytochemicals. This might pave the path for developing a scientifically validated botanical or lead to semisyntheic derivatives intended for modern medicine.

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Anti-urolithiatic activity of Solanum nigrum hydroalcoholic extract in ethylene glycol-induced urolithiasis in rats

Cited by 5 publications

References 0 publications

A Survey of Ethnomedicinal Plants used for Urinary Tract Infection (UTI) and Kidney Stone in the Nalbari, Sonitpur and Tinsukia Districts of Assam, India

A Survey of Ethnomedicinal Plants used for Urinary Tract Infection (UTI) and Kidney Stone in the Nalbari, Sonitpur and Tinsukia Districts of Assam, India

An Overview on Pashanabedha Medicinal Plants

Ethnomedicinal study of medicinal plants used by Mizo tribes in Champhai district of Mizoram, India

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