Anti-tumor target screening of sea cucumber saponin Frondoside A: a bioinformatics and molecular docking analysis
Guangchun Liu,
Shenglin Zhang,
Ruoyan Lin
et al.
Abstract:Cancer remains the leading cause of death worldwide. In spite of significant advances in targeted and immunotherapeutic approaches, clinical outcomes for cancer remain poor. The aim of the present study was to investigate the potential mechanisms and therapeutic targets of Frondoside A for the treatment of liver, pancreatic, and bladder cancers. The data presented in our study demonstrated that Frondoside A reduced the viability and migration of HepG2, Panc02, and UM-UC-3 cancer cell in vitro. Moreover, we uti… Show more
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