Anti-tumor effects of polybutylcyanoacrylate nanoparticles of diallyl trisulfide on orthotopic transplantation tumor model of hepatocellular carcinoma in BALB/c nude mice

Antiproliferative activity of chloroformic extract of Persian Shallot, Allium hirtifolium, on tumor cell lines

“…1 Morphological changes of L929, MCF-7, and HeLa cells after treating with A. hirtifulium extract for 72 h. Shrinkage and detachment effects were visible in treated cells (a, untreated; b, treated cells) Zhang et al 2007). It was shown that concentration and duration of the exposure to allyl sulfides increased the antiproliferative effects.…”

“…This antineoplastic effect was greater for lipidsoluble than for water-soluble allyl sulfides Tattelman 2005). Diallyl disulfide suppresses the growth of human colon tumor cell xenografts in athymic nude mice (Miron et al 2003;Zhang et al 2007).…”

Nutraceuticals and Functional Foods: The Foods for the Future World

“…Several epidemiologic studies have shown that the garlic may be effective in reducing human cancer risk (Dorant et al, 1993). During last decade antitumor activity has been demonstrated against gastrointestinal tract cancer, colon cancer, prostate cancer, mammary carcinoma, hepatocellular carcinoma, lung cancer and sarcoma and squamous cell carcinoma of skin and oesophagus (Kalra et al, 2006;Ban et al, 2007;Kim et al, Zhang et al, 2007;Butt et al, 2009) An investigation conducted in China showed a strong inverse relationship between stomach cancer risk and increasing intake of garlic (You et al, 1988). More recently, in a study of more than 40,000 postmenopausal women, garlic consumption was associated with nearly 50% reduction in colon cancer risk (Steinmetz et al, 1994).…”

Efficacy of Niosomal Formulation of Diallyl Sulfide Against Experimental Candidiasis in Swiss Albino Mice

“…These problems associated with poorly soluble compounds are usually circumvented through the use of an appropriate delivery system that can modify the distribution of the drug in the body and facilitate controlled release and preferential delivery at the site of infection [34][35][36][37].…”