Anti-tick vaccine candidate subolesin is important for blood feeding and innate immune gene expression in soft ticks
Krittika Nandy,
Comfort Tamakloe,
Daniel E. Sonenshine
et al.
Abstract:Subolesin is a conserved molecule in both hard and soft ticks and is considered as an effective candidate molecule for the development of anti-tick vaccine. Previous studies have reported the role of subolesin in blood feeding, reproduction, development, and gene expression in hard ticks. However, studies addressing the role of subolesin in soft ticks are limited. In this study, we report that subolesin is not only important in soft tick Ornithodoros turicata americanus blood feeding but also in the regulation… Show more
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