Anti‐Thermal Skin Aging Activity of Aqueous Extracts Derived from Apple Mint (<i>Mentha suaveolens</i> Ehrh.) in Human Dermal Fibroblasts

Son, Dahee; Kim, Minkyung; Woo, Hyunju; Park, Deokhoon; Jung, Eunsun

doi:10.1155/2018/4595982

Cited by 6 publications

(3 citation statements)

References 32 publications

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“…Furthermore, it has been reported that it possesses various biological properties such as antioxidant, antimicrobial, antifungal, anti-inflammatory, and anticancer [11–13]. In a previous study, we have observed that M. suaveolens extract exerted the antithermal skin-aging effect in human dermal fibroblasts [14]. However, the cytoprotective activity of M. suaveolens against oxidative stress-induced cell damage in keratinocytes has not been reported yet.…”

Section: Introductionmentioning

confidence: 99%

Protective Effects of Aqueous Extract of Mentha suaveolens against Oxidative Stress-Induced Damages in Human Keratinocyte HaCaT Cells

Lee

Yeom

Shin

et al. 2019

Evidence-Based Complementary and Alternative Medicine

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Mentha suaveolens is an aromatic herb that has a wide range of biological activities, including antimicrobial, antifungal, anti-inflammatory, and hepatoprotective properties. Although there are a few reports on the antioxidant property of M. suaveolens, its cytoprotective activity against oxidative stress has not been reported yet. The objective of this study was to determine the protective activity of M. suaveolens aqueous extract (MSAE) against hydrogen peroxide- (H2O2-) induced oxidative stress and apoptosis in human keratinocyte HaCaT cells. MSAE pretreatment decreased H2O2-induced cytotoxicity and suppressed H2O2-induced intracellular ROS generation. Furthermore, MSAE suppressed expression levels of H2O2-induced apoptotic genes such as cleaved caspase-3, caspase-9, and cleaved poly (ADP-ribose) polymerase (PARP). Pretreatment with MSAE induced expression of phase II enzyme such as HO-1 through translocation of NF-E2-related factor (Nrf2) upon H2O2 exposure. These results revealed that the cytoprotective effect of MSAE against oxidative stress-induced cell death was associated with activation of Nrf2-mediated phase II enzyme expression.

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Section: Introductionmentioning

confidence: 99%

Protective Effects of Aqueous Extract of Mentha suaveolens against Oxidative Stress-Induced Damages in Human Keratinocyte HaCaT Cells

Lee

Yeom

Shin

et al. 2019

Evidence-Based Complementary and Alternative Medicine

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“…Apple mint (Mentha suaveolens) essential oil possesses cell regenerative, antioxidant, antiseptic, and insecticidal properties. The oil's anti-aging activity has been demonstrated [35] - [36]. Therefore, this oil and clay mixture could also be an effective aid in acne treatment.…”

Section: Environment Technology Resources Rezekne Latvia Proceedings ...mentioning

confidence: 99%

The Application Perspectives of Lake Clay Infused With Natural Active Agents - Essential Oils in Cosmetology and Dermatology

Tretjakova,

Misiņa,

Deksne

et al. 2024

ETR

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The aim of the research is to experimentally test and scientifically substantiate the mixture of lake clay and a natural active agent – essential oil, in perspective of its application in cosmetology and dermatology. Sensory properties of lake clay and mixtures of lake clay with essential oils were tested. The presence and quantity of Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli, and aerobic mesophilic microorganisms in lake clay and lake clay with essential oils mixtures were determined. Thyme (Thymus vulgaris), apple mint (Mentha suaveolans), and caraway (Carum carvi) essential oils, which not only improve the cosmetic value of the product but also act as antimicrobial agents and preservatives, showed the best results. They meet the requirements of Latvian Cabinet Regulation No. 354 “Procedure for Meeting the Significant Requirements for Cosmetics” and European Standard EN ISO 17516: 2014, Cosmetics - Microbiology - Microbiological limits.

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“…Heat-induced expression of MMP-1, MMP-3, MMP-10, MMP-12, and MMP-13 in human dermal fibroblast was significantly inhibited by 100 μg/mL of apple mint leaves extract (ALE). Also, the activity of p-ERK, p-JNK, p-p38, and the expression of IL-8 were inhibited in a dose-dependent manner in HDF cells treated with ALE [ 183 ].…”

Section: Properties Of the Mentha Genusmentioning

confidence: 99%

The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties

et al. 2021

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: Medicinal plants and their derived compounds have drawn the attention of researchers due to their considerable impact on human health. Among medicinal plants, mint (Mentha species) exhibits multiple health beneficial properties, such as prevention from cancer development and anti-obesity, antimicrobial, anti-inflammatory, anti-diabetic, and cardioprotective effects, as a result of its antioxidant potential, combined with low toxicity and high efficacy. Mentha species are widely used in savory dishes, food, beverages, and confectionary products. Phytochemicals derived from mint also showed anticancer activity against different types of human cancers such as cervix, lung, breast and many others. Mint essential oils show a great cytotoxicity potential, by modulating MAPK and PI3k/Akt pathways; they also induce apoptosis, suppress invasion and migration potential of cancer cells lines along with cell cycle arrest, upregulation of Bax and p53 genes, modulation of TNF, IL-6, IFN-γ, IL-8, and induction of senescence phenotype. Essential oils from mint have also been found to exert antibacterial activities against Bacillus subtilis, Streptococcus aureus, Pseudomonas aeruginosa, and many others. The current review highlights the antimicrobial role of mint-derived compounds and essential oils with a special emphasis on anticancer activities, clinical data and adverse effects displayed by such versatile plants.

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Anti‐Thermal Skin Aging Activity of Aqueous Extracts Derived from Apple Mint (Mentha suaveolens Ehrh.) in Human Dermal Fibroblasts

Cited by 6 publications

References 32 publications

Protective Effects of Aqueous Extract of Mentha suaveolens against Oxidative Stress-Induced Damages in Human Keratinocyte HaCaT Cells

Protective Effects of Aqueous Extract of Mentha suaveolens against Oxidative Stress-Induced Damages in Human Keratinocyte HaCaT Cells

The Application Perspectives of Lake Clay Infused With Natural Active Agents - Essential Oils in Cosmetology and Dermatology

The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties

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