Anti-stress Constituents of Evolvulus alsinoides: An Ayurvedic Crude Drug

Gupta, Prasoon; Akanksha, .; Siripurapu, Kiran B.; Ahmad, Ausaf; Palit, Gautam; Arora, Ashish; Maurya, Rakesh

doi:10.1248/cpb.55.771

Cited by 35 publications

(20 citation statements)

References 24 publications

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“…These alkyl esters show biological activities like antioxidant, anti-stress, anti-aging and they inhibit collagenase, reverse transcriptase and DNA polymerase. [14 -17] On many occasions, methyl caffeoylquinates, [18 -20] ethyl caffeoylquinates, [21] butyl caffeoylquinates, [22] methyl feruloylquinates, [23] methyl dicaffeoylquinates, [15,16,24] butyl dicaffeoylquinates, [25] methyl caffeoyl-sinapoylquinates and ethyl caffeoyl-sinapoylquinates [26] are reported in nature by the tedious isolation and purification methods followed by spectroscopic identification. On occasions methyl quinates might as well be the product formed after methanolic extraction and could frequently be artifacts in plant analysis.…”

Section: Introductionmentioning

confidence: 99%

How to identify and discriminate between the methyl quinates of chlorogenic acids by liquid chromatography–tandem mass spectrometry

Jaiswal

Kuhnert

2011

J. Mass Spectrom.

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The methyl esters of chlorogenic acids, methyl quinates, are widely distributed in plant materials and frequently appear as extraction artifacts in plant samples. This is the first time when liquid chromatography-tandem mass spectrometry methods have been used for the identification and characterization of the methyl quinates. For this purpose, methyl quinates of mono caffeoylquinic acids and mono feruloylquinic acids were synthesized as authentic standards. The methyl quinates of mono and diacyl chlorogenic acids have shown characteristic fragmentation pattern in their tandem mass spectra. MS(n + 1) spectra of the methyl quinates of diacyl chlorogenic acids were identical to MS(n) spectra of mono acyl derivatives. These quinates do not produce any methyl quinate peak at m/z 205 if compared with quinic acid peak at m/z 191 in negative ion mode. In the MS(n) spectra of these quinates, cinnamic acid part or cinnamoyl part was detected as a base peak in negative ion mode. The retention time, order of elution and fragmentation pattern were completely different if compared with LC-MS(n) methods developed for chlorogenic acids. These LC-MS(n) methods have been applied for the identification and regioisomeric characterization of the methyl quinates of chlorogenic acids in maté tea and woodruff (Galium odoratum). Two methyl caffeoylquinates (2 and 4) were identified as methyl 3-caffeoylquinate and methyl 5-caffeoylquinate.

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Section: Introductionmentioning

confidence: 99%

How to identify and discriminate between the methyl quinates of chlorogenic acids by liquid chromatography–tandem mass spectrometry

Jaiswal

Kuhnert

2011

J. Mass Spectrom.

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“…P. Gupta et al () isolated three antistress phenylpropanoids ( 32 – 34 ) from the ethanol extract of E. alsinoides . Among them, evolvoid A ( 32 ) displayed the most promising antistress effect by normalizing hyperglycemia, plasma corticosterone, creatine kinase, and adrenal hypertrophy.…”

Section: Phytochemistrymentioning

confidence: 99%

Medicinal uses, pharmacology, and phytochemistry of Convolvulaceae plants with central nervous system efficacies: A systematic review

Chen

Liu

Yang

et al. 2018

Phytotherapy Research

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Central nervous system (CNS) disorders play a major impact on individual lives and place a severe strain on health care resources. Convolvulaceae is a family comprising approximately 1,600-1,700 species grouped in 55-60 genera, and many species are reported to have an effect on CNS functions. A systematic review of the literature studies was carried out to summarize available evidences on Convolvulaceae plants with CNS efficacies. This review is based on various data sources such as Google Scholar, Web of Science, Scopus, PubMed, and Wanfang Data. A total of 200 related articles were included in this review. According to the research result, 54 Convolvulaceae species are suggested to display CNS efficacies historically, and 46 species have been evaluated for their CNS efficacies. In addition, 67 compounds from 16 Convolvulaceae species are recognized to possess CNS efficacies. Despite great progress made through pharmacology and phytochemistry studies on CNS active Convolvulaceae species, more exploratory research is needed to gain a better understanding of the CNS efficacies of this plant family.

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“…The plant is used in Ayurveda in the treatment of stress, neurodegenerative diseases, amnesia and asthma. Leaves are recommended for asthma and mental disturbances 9,10 .…”

Section: Traditional Usesmentioning

confidence: 99%

A Review on Pharmacognosy and Pharmacology of Evolvulus Alsinoides (L.) L.

Sundaramurthi¹,

Kannan²

2017

Int. Res. J. Pharm.

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Plants are being used as therapeutic agents due to the side effects caused by synthetic drugs. Medicinal plants have been used from ancient time for the treatment and wellbeing of human beings. The metabolites of the plants are considered to be effective in treating many ailments. Various dosage forms and a wide array of extracts have been used in the traditional system of medicine with potent therapeutic activity experimentally and clinically. Evolvulus alsinoides (L). L is a perennial herb with anticonvulsant, nootropic, anti-inflammatory, antimicrobial, antioxidant, anxiolytic, cardioprotective effects and inhibition of lipid peroxidation in pancreas. This review article is a sincere effort to put forward the therapeutical importance and phytochemistry of the plant.

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Anti-stress Constituents of Evolvulus alsinoides: An Ayurvedic Crude Drug

Cited by 35 publications

References 24 publications

How to identify and discriminate between the methyl quinates of chlorogenic acids by liquid chromatography–tandem mass spectrometry

How to identify and discriminate between the methyl quinates of chlorogenic acids by liquid chromatography–tandem mass spectrometry

Medicinal uses, pharmacology, and phytochemistry of Convolvulaceae plants with central nervous system efficacies: A systematic review

A Review on Pharmacognosy and Pharmacology of Evolvulus Alsinoides (L.) L.

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