2008
DOI: 10.1590/s1678-91992008000400009
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Anti-snake venom: use and adverse reaction in a snake bite study clinic in Bangladesh

Abstract: Snakebites can present local or systemic envenomation, while neurotoxicity and respiratory paralysis are the main cause of death. The mainstay of management is anti-snake venom (ASV), which is highly effective, but liable to cause severe adverse reactions including anaphylaxis. The types of adverse reaction to polyvalent anti-snake venom have not been previously studied in Bangladesh. In this prospective observational study carried out between 1999 and 2001, in the Snake Bite Study Clinic of Chittagong Medical… Show more

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Cited by 38 publications
(21 citation statements)
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“…For the same reason, males were more afflicted with bites than females. Similar results have been reported by many studies in Africa and Asia (18,21,(26)(27)(28).…”
Section: Discussionsupporting
confidence: 91%
“…For the same reason, males were more afflicted with bites than females. Similar results have been reported by many studies in Africa and Asia (18,21,(26)(27)(28).…”
Section: Discussionsupporting
confidence: 91%
“…14 The severity of a venomous bite is more dangerous than the antivenom if it remains untreated, while active management of venomous snakebites through proper guidelines should be practiced without fear. 15 Most of the cases that we came across during our study were of poisonous type 71.5%, which is almost similar to the result that was seen in the study done by Punde DP which showed 67.5% cases of poisonous type of snakebite. 16 Laboratory investigations like bleeding time and clotting time were done and also patient was assessed clinically for the type of snake bite prior to the administration of ASV.…”
Section: Discussionsupporting
confidence: 90%
“…7 The percentage of anti-snake venom reaction cases was much higher up to 88.57%, pyrogenic reaction was 80.64% and anaphylaxis was 64.51%. 8 Delayed reaction in the form serum sickness was not reported in our study. The criteria to define serum sickness were pre-defined as three or more of fever, erythematous rash, urticaria myalgia, arthralgia, headache, malaise, nausea and vomiting 5-20 days post-antivenom.…”
Section: Discussioncontrasting
confidence: 50%
“…Nearly 80% of anaphylactic reactions were due to urticaria. 8 All reactions had occurred within 30minutes of the commencement of ASV. Reactions had started as early as 4 minutes of starting ASV in this group.…”
Section: Discussionmentioning
confidence: 99%