Abstract:The compuond EMEB has got a definite anti-Rhinovirus activity on both HRV14 (group A) and HRV39 (group B). The specific activity is lower than that found for Pirodavir used as a positive control, but, since the cytotoxic activity of EMEB on human HeLa cells is more favourable than that of Pirodavir (50 µg/ml against 3 µg/ml), the final Protection Index is higher for EMEB (> 700) as compared to Pirodavir (250). EMEB seems to be stable in aqueous solutions, since its activity after 10 days was unchanged. When EM… Show more
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