Abstract:Background: Phospholipase A2 receptor (PLA2R), an IgG4 subclass antibody, is being extensively studied for diagnosis, monitoring and prognostication of cases of primary membranous nephropathy (MN). There is significant heterogeneity within the studies with most of the work targeted towards circulating PLA2R antibody. The present study evaluates PLA2R glomerular staining in primary MN as a diagnostic test in conjunction with the serology.Methods: Diagnostic study. We studied paraffin-embedded kidney biopsies of… Show more
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