Abstract:Different flavonoid compounds can reduce high‐protein oedemas. The aim of this study was to evaluate the effect of hidrosmin, a synthetic flavonoid, on thermal injury oedema and acute lymphoedema in the hind leg of rats.
Immersion of the right hind leg, up to the knee joint, in a water bath at 55°C for 1 min induced oedematous swelling that increased the leg volume by 17.5 ± 1.5 and 26.6 ± 1.6% after 2 and 4h, respectively. Administration of hidrosmin (25, 50 and 100 mg kg−1, i.v.), 1 h before and 1 h after th… Show more
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