Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report

Pan, Kwang Hyun; Kim, Jin Hee; Kim, Byung Jo; Lee, Chan Nyoung

doi:10.12779/dnd.2015.14.4.176

Cited by 1 publication

(1 citation statement)

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“…The authors specifically investigated mathematic computations with the TMT-A and B, reporting intact performance respect to the premorbid status. In another paper [9], the authors reported the case of a 44-year-old mathematics teacher affected by NMDA encephalitis, that presented dyslexia, phonemic paraphasia, and dyscalculia. In this person all symptoms improved gradually after treatment and, 6 months later, she was able to go back to teach students.…”

Section: Discussionmentioning

confidence: 99%

I can’t count, but I can beat you playing cards: a case report on autoimmune encephalitis

et al. 2021

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Background Autoimmune encephalitis (AE) is a rare inflammatory disorder characterized by important psychiatric and neurologic symptoms. The literature documents high rates of neuropsychological dysfunction in N-methyl D-aspartate-receptor (NMDAr) encephalitis but papers don’t consider specifically calculation disturbances between the long-term deficits, although deficits in executive control and episodic memory were less likely to resolve. Case report Here we present a severe case of NMDAr encephalitis in a young patient without a relevant past medical history. Upon first examination he presented psycho-motor slowdown, speech disorders, severe cognitive deficits in all areas: concentration, attention, memory, language, dual task functions, increased latency in responses, severe dyscalculia. Upon first evaluation, the young patient underwent a battery of neuropsychological tests and he showed a dysexecutive syndrome with performances significantly low for age and education. Our patient hence underwent 1 month of intensive cognitive rehabilitation. After the rehabilitation treatment, he presented an amelioration in all domains except calculations. Conclusions In our patient the calculation disorder has proved to be the most relevant problem and the most difficult to treat. Clinicians should consider a careful approach to determine the prognosis of this syndrome because of the wide range of deficits, the need of prolonged treatment and the rate of long-term sequelae.

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Section: Discussionmentioning

confidence: 99%