Abstract:Although the immunomodulatory effects of Astragali Radix extract (AR) have been documented, its anti-mutagenic activity, a problem arising from chemotherapeutic agents, is rarely reported. Therefore, the anti-mutagenic and immunomodulatory effects of AR were investigated using a cyclophosphamide (CPA)-induced immunosuppressed mouse model to develop an alternative immunomodulatory agent. The fluid-bed-dried aqueous extract of AR containing 37.5% dextrin and exopolymers purified from Aureobasidium pullulans SM-2… Show more
“…In Park et al's study, the antimutagenic and immunomodulatory effects of astragalus root were evaluated using a cyclophosphamideinduced immunosuppressed mouse model to develop an alternative immunomodulatory agent. The results obtained show that astragalus root, at an appropriate oral dose, could act as an alternative agent with significant antimutagenic and immunomodulatory properties [8].…”
Bioactive components are substances that positively influence the organism, resulting in a physiological benefit and/or reduction in the risk of developing certain pathologies [...]
“…In Park et al's study, the antimutagenic and immunomodulatory effects of astragalus root were evaluated using a cyclophosphamideinduced immunosuppressed mouse model to develop an alternative immunomodulatory agent. The results obtained show that astragalus root, at an appropriate oral dose, could act as an alternative agent with significant antimutagenic and immunomodulatory properties [8].…”
Bioactive components are substances that positively influence the organism, resulting in a physiological benefit and/or reduction in the risk of developing certain pathologies [...]
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.