Anti‐Mullerian hormone and its relationship to ovulation response and fertility in timed AI Bos indicus heifers

Abstract

This study evaluated the association between plasma anti‐Mullerian hormone (AMH) concentration and fertility in Nelore (Bos indicus) heifers submitted to timed artificial insemination (TAI). At the onset of the synchronization protocol, heifers (n = 289) received a subcutaneous P4 ear implant (3 mg) and 2 mg of oestradiol benzoate. Eight days later, the P4 implant was removed and 0.5 mg of oestradiol cypionate, prostaglandin (0.265 mg, i.m.) and equine chorionic gonadotropin (300 UI, i.m.) was administered, and TAI was performed 48 hr after ear implant removal. Ovarian ultrasound evaluations were performed to measure number of ovarian follicles, dominant follicle size and ovulation response. Pregnancy diagnosis was performed by ultrasound 30 days after AI. Heifers with greater circulating AMH had more antral follicles, a smaller dominant follicle near timed ovulation and lower ovulation response to the timed AI protocol compared to heifers with lower circulating AMH. Although AMH and pregnancy outcome had a quadratic‐shaped pattern, AMH was not significantly associated with fertility. In conclusion, heifers with lower AMH had larger follicles towards the end of the synchronization protocol and greater ovulation responses, whereas greater circulating AMH was unrelated to conception success.

Genetic Parameters and Genome-Wide Association Studies for Anti-Müllerian Hormone Levels and Antral Follicle Populations Measured After Estrus Synchronization in Nellore Cattle

“…The circulating concentrations of AMH are highly variable among mammalian species. In the current study, the AMH mean agreed with Zebu cattle reports, which ranged from 1.20 to 1.60 ng/mL [21,24,48]. These values were higher when compared with those reported for Taurine breeds (0.78 ng/mL [52]).…”

“…In vitro fertilization and cattle embryo production are common practices in beef cattle production systems, especially in Zebu breeds [ 13 , 14 , 15 ]. The measurement of AMH concentration and its association with reproductive and fertility traits were widely studied in livestock, including cattle [ 16 , 17 , 18 , 19 , 20 , 21 ]. These studies indicated that circulating AMH levels are a useful indicator of fertility and reproductive performance.…”

Serum concentration of anti-Müllerian hormone and its relationship with ovarian reserve in Brahman oocyte donors

“…Se ha propuesto también la AMH como un marcador para predecir el desempeño de la PEIV en Bos taurus (25,26) y Bos indicus, como la raza Nelore (27,28,29). De esta forma, la AMH como marcador endocrino de la PFA, puede ser útil para seleccionar hembras donantes con alto potencial reproductivo y garantizar una mayor eficiencia en la producción de embriones (22,30).…”

Diet\'s protein supplementation and Haemonchus contortus infection relation to the homeostasis, ovarian gene expression and histology of peripubertal ewes

“…After all, the carryover of chemicals into food products, such as sheep milk and meat, is increasing concerns of public health. Also, because one of the reproductive indicators we evaluated is serum AMH concentration and, synchronisation programs might reverse the possible association between AMH and patterns of follicle growth (Batista et al, 2020;Ribeiro et al, 2014). Moreover, Morotti et al, (2017) found that AMH concentrations, according to progesterone above or below one ng/mL were not different.…”