Anti-microfouling properties of compounds isolated from several Mediterranean Dictyota spp.

Othmani, Ahlem; Bouzidi, Naïma; Viano, Yannick; Alliche, Zahia; Seridi, Halima; Blache, Yves; Hattab, Mohamed El; Briand, Jean‐François; Culioli, Gérald

doi:10.1007/s10811-013-0185-2

Cited by 16 publications

(23 citation statements)

References 58 publications

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“…Bacterial growth inhibition and viability assays were performed based on previous studies of our group (Othmani et al 2014;Camps et al 2011). The microtiter plates were filled as for the antiadhesion assay.…”

Section: Toxicity Assaysmentioning

confidence: 99%

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Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds

Réveillon

Tunin-Ley²,

Grondin³

et al. 2018

J Appl Phycol

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Marine microalgae and cyanobacteria have largely been studied for their biotechnological potential and proved their ability to produce a wide array of bioactive molecules. We investigated the antifouling potential of unexplored benthic tropical microalgae using anti-adhesion and toxicity bioassays against two major micro-and ma crobiofoulers, namely bacteria and barnacles. Fifty strains belonging to six phyla [Cyanobacteria, Miozoa (Dinoflagellata), Bacillariophyta, Cryptophyta, Rhodophyta and Haptophyta] were isolated from southwestern Islands of the Indian Ocean. They were chosen in order to represent as much as possible the huge biodiversity of such a rich tropical ecosystem. The associated chemodiversity was highlighted by both NMR-and LC-MS-based metabolomics. The screening of 84 algal fractions revealed that the anti-adhesion activity was concentrated in methanolic ones (i.e. 93% of all active fractions). Our results confirmed that microalgae constitute a promising source of natural antimicrofoulants as 17 out of the 30 active fractions showed high or very high capacity to inhibit the adhesion of three biofilm-forming marine bacteria. Dinoflagellate-derived fractions were the most active, both in terms of number and intensity. However, dinoflagellates were also more toxic and may not be suitable as a source of environmentally friendly antifouling compounds, in contrast to diatoms, e.g. Navicula mollis. The latter and two dinoflagellates of the genus Amphidinium also had interesting antisettlement activities while being moderately toxic to barnacle larvae. Our approach, combining the bioprospecting of a large number of tropical microalgae for their anti-settlement potential and metabolomics analyses, constituted a first step towards the discovery of alternative ecofriendly antifoulants.

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Section: Toxicity Assaysmentioning

confidence: 99%

“…A collection of fifty strains covering six different phyla (Table 1) was screened to study their AF properties. To this end, we used a bioassay targeting the anti-adhesion activity against three marine biofilm-forming bacteria that was designed to discover effective antimicrofouling compounds (Camps et al 2011;Othmani et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds

Réveillon

Tunin-Ley²,

Grondin³

et al. 2018

J Appl Phycol

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“…As part of our ongoing research on phytochemical investigation of brown algae (Bouzidi et al, 2008;El Hattab et al, 2008Mokrini et al, 2008;Viano et al, 2011;Othmani et al, 2014), the present paper describes the chemical analysis of organic extracts obtained from Mediterranean samples of C. foeniculacea collected off the Algerian coasts. This work highlights the absence of terpenoids and allows the isolation and characterization of three known sterols, fucosterol (1) and saringosterols (2 and 3) (Fig.…”

Section: Introductionmentioning

confidence: 99%

Sterols from the brown alga Cystoseira foeniculacea: Degradation of fucosterol into saringosterol epimers

Bouzidi

Viano

Ortalo-Magné

et al. 2019

Arabian Journal of Chemistry

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The present study was carried out in order to determine the phytochemical composition of the marine brown alga Cystoseira foeniculacea collected off the coasts of Algeria. After a preliminary fractionation of its organic crude extracts by column chromatography, the resulting fractions were further analysed by 1 H NMR. Even though algal species of the genus Cystoseira are commonly known to produce a wide variety of meroditerpenoids, in the case of C. foeniculacea none of the fractions were found to contain such compounds: most of the fractions showed typical 1 H NMR signals of fatty acids and derivatives (mainly glycerolipids and glycolipids). Nevertheless, the thorough analysis of a sterol-enriched fraction by RP-C 8 HPLC led to the isolation, for the first time from this species, of fucosterol (1) and a mixture of saringosterols (2 and 3). The NMR data of compounds 1-3 were fully determined with the help of 1D and 2D experiments which allowed the reassignment of some attributions in comparison with those reported in the literature. This work also confirms evidence of the oxidative degradation of fucosterol into a C-24 epimeric mixture of saringosterols. ª 2014 Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

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Section: Introductionmentioning

confidence: 99%

“…Among brown algae, Dictyota species are the best wellstudied sources of secondary metabolites, and the ecological function and biological activities of these compounds are deeply studied (Viano et al 2009;Rasher and Hay 2010;Rasher et al 2011;Othmani et al 2014). Dictyota is particularly rich in bioactive terpenes (Viano et al 2009;Othmani et al 2014;da Gama et al 2014) of which some have an established potential for anti-fouling coatings, thanks to their algicidal (Kim et al 2006), anti-bacterial (Enoki et al 1983) and anti-fungal (Tringali et al 1986) and molluscicidal activity (Tringali et al 1986; Barbosa et al 2007). Dictyotalean diterpenes also have been identified as potential therapeutic options for different pathologies (Abou-El-Wafa et al 2013;Caamal-Fuentes et al 2014), HIV-1 and HSV-1, thanks to their anti-retroviral (Pereira et al 2004;Abrantes et al 2010;Cavalcanti et al 2011;Miceli et al 2012;Zhou et al 2013), anti-leishmaniasis (Soares et al 2012) and anti-malarial activity (Jongaramruong and Kongkam 2007) and their role as anti-coagulants (De Andrade et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Abiotic regulation of growth and fertility in the sporophyte of Dictyota dichotoma (Hudson) J.V. Lamouroux (Dictyotales, Phaeophyceae)

2016

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While Dictyota dichotoma has been cultured for decades, relatively little is known on the abiotic regulation of its growth, life cycle and release periodicity. Here, we evaluated the different abiotic factors that potentially control growth, survival, fertility and spore release in order to establish efficient culture methods of the sporophyte that allow life cycle control. Vegetative growth is maximal at room temperature (18-20°C), but cultures can be stored for months at low temperatures (≈8°C). Red light, increased temperature and nutrient manipulation proved to be excellent triggers inducing sporogenesis. Sporophytes lack any lunar periodicity in spore release in contrast to gametophytes, but surprisingly, release of meiospores follows a similar diurnal cycle. This enables the production of synchronously developing spores during the entire lunar cycle. Interest in this species relates to its potential for commercial applications for phytoremediation, metabolites with therapeutic and anti-biofouling potential, and its usage as a model for developmental research complementary to Fucus.

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Anti-microfouling properties of compounds isolated from several Mediterranean Dictyota spp.

Abstract: International audienceno abstrac

Cited by 16 publications

References 58 publications

Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds

Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds

Sterols from the brown alga Cystoseira foeniculacea: Degradation of fucosterol into saringosterol epimers

Abiotic regulation of growth and fertility in the sporophyte of Dictyota dichotoma (Hudson) J.V. Lamouroux (Dictyotales, Phaeophyceae)

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