“…All selected articles evaluated the efficacy of different antimicrobial agents present in dentifrice formulations. Ten authors [ 9 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ] evaluated dentifrices with chemical antimicrobial agents, nine authors [ 1 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ] evaluated dentifrices with herbal antimicrobial agents and twenty authors [ 2 , 6 , 11 , 12 , 18 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 ] evaluated both chemical and herbal agents.…”