Anti-malarial, anti-inflammatory and antioxidative activities of the aqueous extract of <em>Picralima nitida</em> (STAPF) TH. &H. Durand fruits (Apocynaceae) in rats
Abstract:Malaria is a life-threatening disease generating secretion of cytokines and inflammatory mediators that trigger inflammatory reactions and oxidative stress often leading to severe forms of the disease. The study investigates the anti-malarial, anti-inflammatory and antioxidative effects of the aqueous extract of Picralima nitida fresh fruits in Plasmodium berghei-induced malaria in rat. Malaria was induced by intraperitoneal inoculation of 500 μl of 1x10 6 Plasmodium berghei-parasitized erythrocytes. Parasitae… Show more
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