Anti‐Lu 11: Another Antibody Defining a High‐Frequency Antigen Related to the Lutheran Blood Group System<sup>1</sup>

Gralnick, Mary Ann; Goldfinger, Dennis; Hatfield, Patricia A.; Reid, Marion E.; Marsh, W. L.

doi:10.1111/j.1423-0410.1974.tb02388.x

Cited by 12 publications

(7 citation statements)

References 11 publications

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“…Because all the other antigens were associated with single‐point mutations or small deletions, there is a possibility that LU11 was not a part of Lutheran system. Although there are at least three examples of LU:−11 individuals, there is no evidence that LU11 is inherited 18,19 …”

Section: Discussionmentioning

confidence: 99%

Molecular bases of the antigens of the Lutheran blood group system

Crew

Green²,

Daniels³

2003

Transfusion

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Section: Discussionmentioning

confidence: 99%

Molecular bases of the antigens of the Lutheran blood group system

Crew

Green²,

Daniels³

2003

Transfusion

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“…Lu11: Gralnick and colleagues 33 described the first example of anti-Lu11. Anti-Lu11 was present in the serum of a Caucasian woman who had four children and a history of transfusion.…”

Section: The Expanding Lutheran Systemmentioning

confidence: 99%

The Lutheran blood group system: a review

Beck¹

1998

Immunohematology

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At first sight, the Lutheran system would seem to have little interest to blood bankers. Lutheran antibodies are rarely, if ever, clinically relevant, although their identification has the potential to be enormously time-consuming. However, other complexities of this system are proving to be extraordinarily intricate. Genetically, the system appears to be composed of at least three closely linked loci, each with two alleles and, so far, 20 antigens, which have laid claim to at least an honorary affiliation.Two antigens, Lu10 and Lu15, have become obsolete.Three different interpretations of the genetic events leading to the Lu null phenotypes have been needed to accommodate the hereditary observations. The biochemistry of the cell membrane structures on which Lutheran antigenic activity resides is starting to be unravelled. Information about Lutheran has been accumulating for 50 years.This review will summarize what is known to date.

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“…The three family members who are Lu(a-b -) are also Lu:-3, -4, -5, -6, -7, -8, -9, -11, -12, -13, while the remaining members are Lu: 3,4,5,6,7,8,11,12,13. None of the family possesses the uncommon antigen Lu9.…”

Section: Serological Findingsmentioning

confidence: 99%