Anti-leishmanial activity of Eleutherine plicata Herb. and predictions of isoeleutherin and its analogues
Kelly Cristina Oliveira de Albuquerque,
Andreza do Socorro Silva da Veiga,
Fernando Tobias Silveira
et al.
Abstract:Introduction: Leishmaniasis is caused by protozoa of the genus Leishmania, classified as tegumentary and visceral. The disease treatment is still a serious problem, due to the toxic effects of available drugs, the costly treatment and reports of parasitic resistance, making the search for therapeutic alternatives urgent. This study assessed the in vitro anti-leishmanial potential of the extract, fractions, and isoeleutherin from Eleutherine plicata, as well as the in silico interactions of isoeleutherin and it… Show more
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