Anti-LDL antibody-nanoparticles embedded cryogel for low density lipoprotein-depletion from hypercholesterolemic human serum

Yavuz, Serpil Özkara; Ünlüer, Özlem Biçen; Ersöz, Arzu; Say, Rıdvan

doi:10.1080/01496395.2019.1612912

Cited by 3 publications

(2 citation statements)

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“…Besides these, modification of the macropores requires mild conditions, which leads them to be used widely in separation techniques, flow synthesis, and membrane studies. [42][43][44][45] In this study, nano-FDH mimic enzyme was synthesized and used in a reactor system to improve and preserve the stability and reactivity of the natural enzyme in the continuous conversion of CO 2 to formic acid. Flow conversion offers many advantages in terms of control, safety, efficiency, and flexibility, making it a valuable technique for both research and industrial applications.…”

Section: Introductionmentioning

confidence: 99%

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Formate dehydrogenase mimic nanoenzyme embedded cryogel for CO₂ conversion

Biçen Ünlüer,

Sümbelli,

Hür

et al. 2023

Polymers for Advanced Techs

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CO2 conversion to formic acid in a single‐step reaction was investigated by incorporating MoSe2 nanoparticles into a cryogel‐based reactor system, resulting in a formate dehydrogenase (FDH) enzyme‐mimicking system. MoSe2 nanoparticles were synthesized via the microwave synthesis method, and they took part as the cofactor of the enzymatic system. Following, in combination with MACys‐Ru(bipyr)2‐MACys, MoSe2 nanoparticles were used as the cofactor of the conversion reaction in the MACys‐Ru(bipyr)2‐MACys‐co‐p(HEMA) cryogel column‐based reactor system. Synthesized nanoparticles were characterized by Fourier transformed infrared spectroscopy, field emission‐scanning electron microscopy, transmission electron microscopy, and energy dispersive x‐ray spectroscopy. The conversion reaction was monitored using high‐pressure liquid chromatography, and the parameters affecting the conversion yield (e.g., pH change and reusability of the reactor) were investigated. The results showed that the obtained mimic FDH‐based CO2 conversion column system worked like a reactor in the conversion of CO2 into formic acid. Besides, the developed cryogenic reactor provided a reusable single‐step conversion reaction with a high yield at room temperature in mild conditions.

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Section: Introductionmentioning

confidence: 99%

“…The interconnected macroporous structure of the cryogels allows higher flow rates without any clogging and backpressure. Besides these, modification of the macropores requires mild conditions, which leads them to be used widely in separation techniques, flow synthesis, and membrane studies 42–45 …”

Section: Introductionmentioning

confidence: 99%