Anti-Inflammatory Properties of a Colored Avocado Seed Extract

Dabas, Deepti; Ziegler, Gregory R.; Lambert, Joshua D.

doi:10.17140/aftnsoj-5-151

Cited by 8 publications

(7 citation statements)

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“…In another approach, Dabas et al confirmed this anti-inflammatory activity by anin vitroassay. The research group used an extract of the avocado seed on lipopolysaccharide (LPS)-induced inflammatory responses of murine macrophages, which revealed a reduction in the production of the inflammatory factors significantly [107].…”

Section: Drugs and Bioactive Compoundsmentioning

confidence: 99%

Persea Americana Agro-Industrial Waste Biorefinery for Sustainable High-Value-Added Products

et al. 2021

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Significant problems have arisen in recent years, such as global warming and hunger. These complications are related to the depletion and exploitation of natural resources, as well as environmental pollution. In this context, bioprocesses and biorefinery can be used to manage agro-industrial wastes for obtaining high-value-added products. A large number of by-products are composed of lignin and cellulose, having the potential to be exploited sustainably for chemical and biological conversion. The biorefinery of agro-industrial wastes has applications in many fields, such as pharmaceuticals, medicine, material engineering, and environmental remediation. A comprehensive approach has been developed toward the agro-industrial management of avocado (Persea americana) biomass waste, which can be transformed into high-value-added products to mitigate global warming, save non-renewable energy, and contribute to health and science. Therefore, this work presents a comprehensive review on avocado fruit waste biorefinery and its possible applications as biofuel, as drugs, as bioplastics, in the environmental field, and in emerging nanotechnological opportunities for economic and scientific growth.

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Section: Drugs and Bioactive Compoundsmentioning

confidence: 99%

Persea Americana Agro-Industrial Waste Biorefinery for Sustainable High-Value-Added Products

et al. 2021

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“…Concerning extraction, ultrasound-assisted extraction has been also employed, observing different results; i.e., the highest color intensity and the phenolic content were obtained in parallel at 40 • C using methanol as the solvent [98]. This technology was also applied to recover a colored extract from avocado stone with in vitro antioxidant and cancer inhibitory activity, and so it can be regarded as a functional food ingredient or as a source of novel natural antioxidants and anticancer compounds [99].…”

Section: Extraction Of An Orange Colorantmentioning

confidence: 99%

“…using methanol as the solvent [98]. This technology was also applied to recover a colored extract from avocado stone with in vitro antioxidant and cancer inhibitory activity, and so it can be regarded as a functional food ingredient or as a source of novel natural antioxidants and anticancer compounds [99].…”

Section: Extraction Of An Orange Colorantmentioning

confidence: 99%

Avocado-Derived Biomass as a Source of Bioenergy and Bioproducts

2020

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The avocado (Persea americana Mill.) is a tree native to Mexico and Guatemala. Avocado consumption, fresh or in the form of processed products, is growing everywhere and it has caused a large number of countries to invest heavily in avocado production. The industrialization of avocado gives as a result a huge amount of waste, not only the peel and stone but also that waste generated by the pruning practices and oil extraction. These biomasses could be converted into raw materials to obtain different types of co-products, but this implies changes in the use of these resources, the design of efficient production systems, and integration to take full advantage of them, e.g., by developing biorefinery models. Therefore, this review firstly gives a snapshot of those residues generated in the avocado industry and provides their chemical composition. Secondly, this review presents updated information about the valorization ways of avocado-derived biomass to obtain bioenergy, biofuels, and other marketable products (starch, protein, phenolic compounds, and biosorbents, among others) using a single process or integrated processes within a biorefinery context. Green technologies to obtain these products are also covered, e.g., based on the application of microwaves, ultrasound, supercritical fluids, etc. As a conclusion, there is a variety of ways to valorize avocado waste in single processes, but it would be promising to develop biorefinery schemes. This would enable the avocado sector to move towards the zero-waste principle.

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“…In addition, the structure of a natural colorant (glycosylated benzotropolone) has recently been identified in the stone and it showed anti-inflammatory activity [11,21] (Figure 2). The the active fractions with trypanocidal activity against Trypanosoma cruzi, the etiological agent for Chagas' diseases, included 1,2,4-trihydroxyheptadecane and 1,2,4-trihydroxynonadecane derivatives [6] ( Figure 2).…”

Section: Phytochemicalsmentioning

confidence: 99%

“…Pharmacological actions such as antioxidant activity, hypotensive, anti-analgesic, anti-inflammatory, skin disorder treatment, photoprotective effect against UVB radiation, antivirals, antifungals, antioxidants, etc. are being related to their bioactive compound, such as phenolic compounds [3,4]. Therefore, besides to avocado fruit and oil, avocado waste extracts could promote the development of functional ingredients for applications in the food, nutraceutical, pharmaceutical and cosmetic sectors.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Bio-Compounds from Avocado Residual Biomass

García-Vargas

Contreras

Castro

2020

The 1st International Electronic Conference on Biomolecules: Natural and Bio-Inspired Therapeutics for Human Diseases

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Since ancient times, plants have been used as preservatives, spices, flavorings and as natural remedies to prevent or treat diseases owing to the biological activity correlated with the bioactive compounds they contain. The avocado fruit (Persea americana), native to Mexico and Guatemala, has been traditionally used for its pleasant organoleptic characteristics, high nutritional value and health benefits, but its residual biomass (seeds, skin and tree leaves) is also valuable in therapeutic terms. For this reason, the present investigation reviews the pharmacological potential of avocado waste. It can serve as a source of antioxidants, as well as hypotensive, anti-analgesic, photoprotective, antibacterial, and anti-inflammatory agents, and can be used to treat skin disorders. The main active components seem to be phenolic compounds. The content of phenolic compounds in waste extracts varied from 6 to 307 g/kg dry weight, depending on the waste type and extraction conditions, among others. In particular, our results suggested that using water as a solvent, a high amount of phenolic compounds can be obtained from the peel (266 g/kg dry weight), and this was correlated with major antioxidant activity. Therefore, the peels can be applied to obtain antioxidants, and water can be used as an environmentally friendly extraction solvent to obtain various valuable compounds of its chemical composition for food and pharmacological applications.

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Anti-Inflammatory Properties of a Colored Avocado Seed Extract

Cited by 8 publications

References 0 publications

Persea Americana Agro-Industrial Waste Biorefinery for Sustainable High-Value-Added Products

Persea Americana Agro-Industrial Waste Biorefinery for Sustainable High-Value-Added Products

Avocado-Derived Biomass as a Source of Bioenergy and Bioproducts

Therapeutic Bio-Compounds from Avocado Residual Biomass

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