Anti-inflammatory potential of digested <i>Brassica</i> sprout extracts in human macrophage-like HL-60 cells

García-Ibáñez, Paula; Núñez‐Sánchez, María Ángeles; Oliva-Bolarín, Alba; Martínez-Sánchez, María Antonia; Ramos‐Molina, Bruno; Ruiz–Alcaraz, Antonio J.; Moreno, Diego A.

doi:10.1039/d2fo02914f

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Cellular Models Used To Test the Functionality Of The Intest...1

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2023

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“…Finally, neutrophil activity may be investigated thanks to the use of the HL-60 promyelocytic leukemia cell line able to differentiate into neutrophilic promyelocyte in an appropriate RPMI-1640 medium containing FBS, L-glutamine and HEPES ( Table 3 ). HL-60 cells are also used as a macrophage-like cell model to study the anti-inflammatory potential of bioactive compounds [ 134 ].…”

Section: Cellular Models Used To Test the Functionality Of The Intest...mentioning

confidence: 99%

Complexification of In Vitro Models of Intestinal Barriers, A True Challenge for a More Accurate Alternative Approach

Haddad

Sztupecki

Delayre-Orthez

et al. 2023

IJMS

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The use of cell models is common to mimic cellular and molecular events in interaction with their environment. In the case of the gut, the existing models are of particular interest to evaluate food, toxicants, or drug effects on the mucosa. To have the most accurate model, cell diversity and the complexity of the interactions must be considered. Existing models range from single-cell cultures of absorptive cells to more complex combinations of two or more cell types. This work describes the existing solutions and the challenges that remain to be solved.

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Section: Cellular Models Used To Test the Functionality Of The Intest...mentioning

confidence: 99%

Complexification of In Vitro Models of Intestinal Barriers, A True Challenge for a More Accurate Alternative Approach

Haddad

Sztupecki

Delayre-Orthez

et al. 2023

IJMS

View full text Add to dashboard Cite

show abstract

Anti-inflammatory potential of digested Brassica sprout extracts in human macrophage-like HL-60 cells

Abstract: Cruciferous vegetables have been reported to be a great source of anti-inflammatory compounds. Specifically, sprouts from the Brassicaceae family stand out for their high content in glucosinolates (and their bioactive...

Cited by 1 publication

References 46 publications

Complexification of In Vitro Models of Intestinal Barriers, A True Challenge for a More Accurate Alternative Approach

Complexification of In Vitro Models of Intestinal Barriers, A True Challenge for a More Accurate Alternative Approach

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