Anti-inflammatory effect on genes expression after four days of Qigong training in peripheral mononuclear blood cells in healthy women

Półrola, Paweł; Wilk-Frańczuk, Magdalena; Wilczyński, Jacek; Nowak-Starz, Grażyna; Góral-Półrola, Jolanta; Chruściński, Grzegorz; Bonisławska, Iwona; Pedrycz, Agnieszka; Żychowska, Małgorzata

doi:10.26444/aaem/85208

Cited by 12 publications

(7 citation statements)

References 33 publications

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“…11 As outlined by Feng et al 6 while not well studied in the West, Qigong and its many variants are exercises that have been used to promote health for more than 5000 years with generally favourable results relevant to long COVID recovery in particular, as well as secondary COVID infections. This ancient component of traditional Chinese Medicine, 15,16 which involves a series of breathing exercises, 17 as well as meditation, and gentle body movements to achieve its aims, 15 and is designed to help the individual to relax the mind and level of excess stress, 18 thus setting the stage for intrinsic healing opportunities and possibly diminishing any prevailing inflammatory responses, 19 and feelings of psychological distress may be of immense benefit in consideration of the fatigue, 'brain fog' symptoms, breathing challenges, and pain that are found in long COVID cases and that are hard to treat in the medical model alone.…”

Section: Search Resultsmentioning

confidence: 99%

“…Półrola et al 19 who aimed to study changes in the expression of genes associated with cellular stress response in peripheral mononuclear blood cells in healthy women before and after a 4 day Qigong training program found results that implied an associated reduction in the inflammatory and intensified anti-inflammatory gene expression post Qigong. As per Holder et al 5 this observation if pursued, may be of high value given that among older adults who exhibit a state of obesity may also be expected to exhibit an associated elevation in their inflammatory state and that can cause defects in immune system cell functioning that lower the body's ability to respond effectively to viral infections.…”

Section: Search Resultsmentioning

confidence: 99%

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Qigong, obesity, and immunity dynamics and its application to long COVID-19 syndrome

Marks¹

2023

AOWMC

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COVID-19, an acute respiratory condition resulting in high rates of excess mortality, particularly among adults in later life remains challenging to prevent uniformly and is now found to induce a series of long term adverse health impacts termed ‘long COVID’ syndrome. But can more be done to avert the risk of COVID-19 and its observed long term impact in older adults? This mini review strove to examine, summarize and synthesize the research base concerning the key risk factors underpinning later life acquisition of COVID-19 and whether an ancient mind body technique known as Qigong may be one possible largely overlooked strategy for promoting immunity and minimizing the related health correlate of obesity that can both raise the risk for severe COVID-19 infections and delay its recovery among older adult survivors. A second was to provide related intervention directives for health professionals working or who are likely to work with this vulnerable population in the future. Using the PUBMED and other leading electronic data bases and the key words: Qigong, Immunity, COVID-19, Long COVID-19, Obesity, Older Adults, a fair number of articles indicate that the practice of Qigong may be very useful as an adjunctive intervention strategy for raising immunity levels and fostering weight control among older adults, especially those survivors suffering from long COVID syndrome who remain at risk for second infections.

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Section: Search Resultsmentioning

confidence: 99%

Section: Search Resultsmentioning

confidence: 99%

Qigong, obesity, and immunity dynamics and its application to long COVID-19 syndrome

Marks¹

2023

AOWMC

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“…In addition, Qi can also induce the apoptosis of prostate cancer cells and breast cancer cells [38,39]. Via evaluating changes in the expression of genes associated with cellular stress response in peripheral mononuclear blood cells in healthy women, significant differential expression in NF-kB, CCL2, IL10, HSF1 and HSPA1A were detected after 4 days of Qigong training [40].…”

Section: Discussionmentioning

confidence: 99%

Exploration of Gene Expression Characters of Mouse M-1 Cells Treated by Qigong

2021

Yoga Phys Ther Rehabil

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Qigong is a traditional method of exercise in China and is effective in maintaining physical and mental health, and even in curing diseases. There are many reports about the beneficial effects of Qigong while the underlying functional mechanism has not been systematically explored at the molecular and cellular levels. In this study, we examined the effect of Qigong on gene expressions of mouse M-1 cells using the quantitative real-time polymerase chain reaction (qRT-PCR) and the transcriptome sequencing technology. Analysis result showed that several genes were upregulated the expression level related to cell proliferation and apoptosis by Qigong treatment. Enrichment analysis of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) of differentially expressed genes (DEGs) showed that DEGs are related to many important signaling pathways in cells such as PI3K/AKT, and up-regulated DEGs are beneficial to cell growth, resistance to oxidative damage and apoptosis in vitro. Our study provided some important molecular insights into the positive effect of Qigong, which will help to comprehensively understand the biological mechanism of Qigong on human health and promote the application of Qigong treatment and the related research.

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“…The deep breathing exercises of Qigong can revive the unutilized respiratory function of the lungs. Qigong breathing practices not only mediate a reduction in the inflammatory but also enhance anti-inflammatory gene expression [14]. Such Qigong-style profound breathing effects upon pulmonary function exhibited statistically improved body mass index (BMI) and vital capacity (VC), as shown by the time-resolved quantitative analysis of diaphragm motion with dynamic chest radiography in a cohort of 174 patients [15].…”

Section: Clinical Significancementioning

confidence: 99%

Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine

Zhang

Loudon

et al. 2019

JFMK

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Rising concerns about the short- and long-term detrimental consequences of administration of conventional pharmacopeia are fueling the search for alternative, complementary, personalized, and comprehensive approaches to human healthcare. Qigong, a form of Traditional Chinese Medicine, represents a viable alternative approach. Here, we started with the practical, philosophical, and psychological background of Ki (in Japanese) or Qi (in Chinese) and their relationship to Qigong theory and clinical application. Noting the drawbacks of the current state of Qigong clinic, herein we propose that to manage the unique aspects of the Eastern ‘non-linearity’ and ‘holistic’ approach, it needs to be integrated with the Western “linearity” “one-direction” approach. This is done through developing the concepts of “Qigong breathing signatures,” which can define our life breathing patterns associated with diseases using machine learning technology. We predict that this can be achieved by establishing an artificial intelligence (AI)-Medicine training camp of databases, which will integrate Qigong-like breathing patterns with different pathologies unique to individuals. Such an integrated connection will allow the AI-Medicine algorithm to identify breathing patterns and guide medical intervention. This unique view of potentially connecting Eastern Medicine and Western Technology can further add a novel insight to our current understanding of both Western and Eastern medicine, thereby establishing a vitality score index (VSI) that can predict the outcomes of lifestyle behaviors and medical conditions.

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Anti-inflammatory effect on genes expression after four days of Qigong training in peripheral mononuclear blood cells in healthy women

Cited by 12 publications

References 33 publications

Qigong, obesity, and immunity dynamics and its application to long COVID-19 syndrome

Qigong, obesity, and immunity dynamics and its application to long COVID-19 syndrome

Exploration of Gene Expression Characters of Mouse M-1 Cells Treated by Qigong

Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine

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