Anti-inflammatory Effect of Fallopia sachalinensis RonseDecr. Fruit

Park, Sungha; Jeong, Jeong Hyeon; Park, Byoung Jun; Jeong, Tae Hwa

doi:10.15230/scsk.2015.41.3.237

Journal of the Society of Cosmetic Scientists of Korea

2015

DOI: 10.15230/scsk.2015.41.3.237

|View full text |Cite

Anti-inflammatory Effect of Fallopia sachalinensis RonseDecr. Fruit

Sungha Park¹,

Jeong Hyeon Jeong²,

Byoung Jun Park³

et al.

Abstract: Abstract:To develop a new anti-inflammation agent for cosmetics, we investigated the anti-inflammatory activity of Fallopia sachalinensis RonseDecr. fruit extracts (FSR). FSR inhibited the pre-inflammatory cytokines (1L-1β, IL-6, TNF-α) and reduced NO production of RAW 264.7 macrophage cells in a dose-dependent manner and decreased the activity to about 51% at a concentration of 100 µg/mL. FSR suppressed not only the mRNA expression of iNOS and COX-2, but also the protein expression of iNOS and COX-2 in macrop… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2019

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Antioxidant Effects of Cinnamomum cassia Bark Extract and its Effectiveness as a Cosmetics Ingredient

Lee¹,

Ryu²

2019

Asian J Beauty Cosmetol

View full text Add to dashboard Cite

Purpose: This study examines potential abilities and commercial values of Cinnamon extract as bioactive and cosmetics ingredients. Methods: Cinnamomum cassia bark was extracted with hot water and 70% ethanol to examine its antioxidant effects through its total polyphenol, flavonoid content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, and (2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) ABTS radical scavenging activity. Also, this study examined its nitric oxide (NO) inhibition effect through RAW 264.7 cells into which inflammatory reaction was induced by lipopolysaccharides (LPS), and antihistamine activity in the RBL-2H3 cells. The antibacterial effects of Cinnamomum cassia bark extract on 8 types of bacteria were also studied. Results: As a result of measuring the antioxidant effect, the total polyphenol contents were 90.12 and 113.07 μg/mL, respectively, while the total flavonoid contents were 36.42 and 54.31 μg/mL, respectively. The DPPH scavenging effect was confirmed as 84.93% in the hot water extract and 90.25% in the ethanol extract for 400 μg/mL. The ABTS radical scavenging effect was 82.20% in the hot water extract and 92.21% in the ethanol extract for 400 μg/ mL. Upon measuring the NO inhibitive effect through the RAW 264.7 cells into which inflammation reaction was induced by LPS, the NO generation decreased to 14.57 μM in the hot water extract and 10.15 μM in the ethanol extract in the concentration of 100 μg/mL. This result, compared to the increase up to 20.11 μM by LPS, shows the NO inhibitive effect of Cinnamoum cassia bark extract. As a result of measuring the antihistamine activity in the RBL-2H3 cells, β-hexosaminidase increased to 176.21% by IgE-NDP whereas it was 117.25% in the hot water extract and 100.09% in the ethanol extract in the concentration of 100 μg/mL, confirming the inhibitive effect on β-hexosaminidase discharge. The antibacterial effect was confirmed on all bacteria through the measurement on the Cinnamomum cassia Bark extract on eight types of bacteria. Particularly, the antibacterial effect of the hot water extract and ethanol extract was found to be high in Staphylococcus epidermidis (S. epidermidis), Pityrosporum ovale (P. ovale). Conclusion: Cinnamomum cassia bark extract is deemed prospective as a natural functional cosmetics' ingredient with excellent antioxidant, anti-inflammatory, antihistamine inhibitive and antibacterial effects.

show abstract

Antioxidant Effects of Cinnamomum cassia Bark Extract and its Effectiveness as a Cosmetics Ingredient

Lee¹,

Ryu²

2019

Asian J Beauty Cosmetol

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Anti-inflammatory Effect of Fallopia sachalinensis RonseDecr. Fruit

Cited by 1 publication

References 5 publications

Antioxidant Effects of Cinnamomum cassia Bark Extract and its Effectiveness as a Cosmetics Ingredient

Antioxidant Effects of Cinnamomum cassia Bark Extract and its Effectiveness as a Cosmetics Ingredient

Contact Info

Product

Resources

About