Anti-inflammatory diterpenoids from Callicarpa randaiensis

Isolation, Characterization, and Structure–Activity Relationship Analysis of Abietane Diterpenoids fromCallicarpa bodinierias Spleen Tyrosine Kinase Inhibitors

“…Callicarpa bodinieri is one of the species in the genus Callicarpa that has been used widely in traditional medicine, for the treatment of inflammation, rheumatism, analgesia, hematemesis, gastrointestinal bleeding, scrofula, and swollen sores . The diverse therapeutic applications of plants in the genus Callicarpa may be attributed to their bioactive constituents, including terpenoids, lignans, glycosides, − flavonoids, phenolic acids, − and their volatile oils. , The diterpenoids isolated from this genus have been reported to have anti-inflammatory activities in different disease models; − however, their target has not been identified.…”