Anti-inflammatory and cicatrizing activities of thymol, a monoterpene of the essential oil from Lippia gracilis, in rodents

Riella, K.R.; Marinho, Renata Ribeiro; Santos, Jessica Silva; Pereira-Filho, Rose Nely; Cardoso, Juliana Cordeiro; Albuquerque‐Júnior, Ricardo Luiz Cavalcanti de; Thomazzi, Sara Maria

doi:10.1016/j.jep.2012.07.028

Cited by 204 publications

(151 citation statements)

References 26 publications

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“…Usnic acid treatment did not affect gametogenesis as it was reported that UA at the concentration 50 μg/mL did not inhibit the growth of another green alga, Chlorella fusca. 48 …”

Section: Usnic Acid Algicidal Agentmentioning

confidence: 99%

Usnic acid biological activity: history, evaluation and usage

Alahmadi

2017

Int J Basic Clin Pharmacol

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Since Usnic acid (UA) was isolated from lichen metabolite in 1844, a lot of studies were conducted on it and now it became commercially available in the market. Its wide availability in different lichen species, being isolated easily, and high purity of the isolated product make it an excellent base for producing new pharmaceuticals. In this review the different usage of UA was summarized. It was utilized as an antioxidant, anti-proliferative, antimicrobial and antiprotozoal, larvicidal and insecticidal, antifungal, antiviral, algicidal, anti-inflammatory, pain-relieving and antipyretic agent. Many adverse effects were associated with using usnic acid, especially at high dose, including; hepatotoxicity, genotoxicity, allergenicity, side effects on the cardiovascular system and adipocytes of fatty tissue. This review aimed to throw the light on the updated biological activities, effectiveness and safety and usage of usnic acid during the last decade.

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“…Usnic acid treatment did not affect gametogenesis as it was reported that UA at the concentration 50 μg/mL did not inhibit the growth of another green alga, Chlorella fusca. 48 …”

Section: Usnic Acid Algicidal Agentmentioning

confidence: 99%

Usnic acid biological activity: history, evaluation and usage

Alahmadi

2017

Int J Basic Clin Pharmacol

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“…In some cases, this compound has inhibited Candida tropicalis at very low concentrations: MIC = 39 µg/mL [101], MIC = 0.12% (v/v) [102] and MIC = 350 µg/mL [103]. The anti-inflammatory and cicatrizing effects of thymol have also proved using rodents as a model study [105].…”

Section: Thymolmentioning

confidence: 99%

Pharmacological activities and medicinal properties of endemic Moroccan medicinal plant Origanum compactum (Benth) and their main compounds

Bouyahya¹,

Guaouguaou²,

Dakka³

et al. 2017

APJTD

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“…Since 16th century, thymol-rich essential oils have been evaluated for their benefits in medicinal application [2,3] as well as for their antimicrobial properties [1,4]. Thymol (1) itself exhibits a large number of biological activities, such as antibacterial [5], antileishmanial [6], antiinflammatory [7], antitumor [8] and aedes aegypti larvicidal [9] properties. Thymol also exhibited insecticidal and genotoxic activities on Drosophila melanogaster [10].…”

Section: Introductionmentioning

confidence: 99%