Anti-inflammatory and antimicrobial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees

Comparative Study on in-Vivo Anti-Inflammatory Potential From Leaves of Methanol and Chloroform Extracts of Azadirachta Indica A. Juss and Justicia Adhatoda in Nepal

“…Similar studies conducted before showed potent anti-inflammatory activity of methanol and chloroform extract of both plants [26][27][28] . …”

Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

“…Notably, vasicinone has been reported for its anti-inflammatory, antimicrobial, antiasthmatic, hepatoprotective and moderate anticancer activity [16]. RLX, a vasicinone analogue is believed to possess potent bronchodilator, antiasthmatic and anti-inflammatory properties [17], and has 6 to 10 times strong bronchodilator and anti-asthmatic properties than aminophylline [18].…”

Chemoselective Cleavage of C(CO)−C Bond: Molecular Iodine‐Catalyzed Synthesis of Quinazolines through sp3 C−H Bond Functionalization of Aryl Methyl Ketones

“…Quinazolines, N‐fused heterocyclic compounds, are a part of many natural products and biologically active molecules. Apart from the antimalarial activity, the quinazoline derivatives show a wide range of biological properties, including anticancer,– antibacterial, anti‐inflammatory,– and antihypertensive activities . The quinazolines moiety forms the framework of several drugs approved by the U.S. Food and Drug Administration (FDA), such as Gefitinib, an EGFR inhibitor, Prazosin, an α‐adrenergic blockers, and Erlotinib, which is used in the treatment of tumor .…”