Anti-inflammatory and anti-oxidant action of tadalafil in testicular regeneration process after heat stress
Fernando Leonel da Silva,
Fernanda Carolina Ribeiro Dias,
Sandra Maria Torres
et al.
Abstract:Tadalafil, a potent phosphodiesterase inhibitor 5 (PDE-5), is commonly used for the management of erectile dysfunction. However, its therapeutic potential extends beyond this indication. This study aimed to investigate the impact of tadalafil on the recovery of testicular parenchyma in male Wistar rats exposed to testicular thermal stress. Fifty-four Wistar rats were subjected to testicular thermal stress and randomly assigned to receive either tadalafil treatment (TAD) or no treatment (control). TAD was admin… Show more
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