Anti-inflammatory, analgesic, antitussive and antipyretic activities of polyphenol-enriched fraction from Nymphaea candida

Preventive Effect of the Total Polyphenols from Nymphaea candida on Sepsis-Induced Acute Lung Injury in Mice via Gut Microbiota and NLRP3, TLR-4/NF-κB Pathway

“…As shown in Figure 1 and Table 1, a total of 14 compounds were identified and deduced, including 10 hydrolyzable tannins and 4 flavonoid glycoside compounds. Some compounds were identified compared with reference substances, such as isostrictiniin, ellagic acid, and nicotiflorin [22].…”

“…Nymphaea candida flower was purchased from Xinjiang Shengxiangcao Co. (Urumqi, China) and identified by Jiang He, a researcher at the Institute of Materia Medica of Xinjiang, and the voucher specimens (20210906N) were stored in the Institute of Materia Medica of Xinjiang. The extraction of NCTP was described in our previously published report [22]. This medicinal material was extracted with 70% ethanol by reflux three times for 1 h each time.…”

“…N. candida has a variety of biological activities, such as antibacterial, anti-inflammatory, hypotensive, hepatoprotective, and neuroprotective effects, and polyphenols are its main characteristic compounds [16,20,21]. Total polyphenols from N. candida (NCTP) have been previously prepared and showed better anti-inflammatory, analgesic, antipyretic, and cough activities [22]. However, whether it has the effect of preventing pneumonia has not been reported in the literature.…”