Anti-inflammatory Activity of Bioactive Compounds from Microalgae and Cyanobacteria by Focusing on the Mechanisms of Action

Tabarzad, Maryam; Atabaki, Vahideh; Hosseinabadi, Tahereh

doi:10.1007/s11033-020-05562-9

Cited by 47 publications

(19 citation statements)

References 74 publications

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“…Microalgae and cyanobacteria serve as a source of bioactive compounds that present immunomodulatory activity, such as amino acids [ 28 , 29 , 30 ], peptides, pigment-protein complex, and exopolysaccharides, the latter known to possess anti-inflammatory, antimicrobial, and antiviral properties [ 1 , 31 , 32 , 33 , 34 ]. The major sugars involved in the composition of polysaccharides are xylose, glucose, mannose, and galactose [ 35 ].…”

Section: Immunomodulatory Activity Of Compounds From Microalgaementioning

confidence: 99%

“…Specifically, sulfated polysaccharides have been associated with blood coagulation, antilipidemic activity, and mainly immunomodulatory activity [ 31 ]. Multiple studies have reported anti-inflammatory properties from Arthrospira/Spirulina , Chlorella vulgaris , Chlorella pyrenoidosa , I sochrysis , Pleurochrysis carterae , Dunaliella , Porphyridium purpureum , and Rhodosorus marinus [ 29 , 35 , 36 , 37 , 38 , 39 ].…”

Section: Immunomodulatory Activity Of Compounds From Microalgaementioning

confidence: 99%

“…Anti-inflammatory, antitumoral, antimicrobial, and antiviral properties from a wide variety of compounds are directly linked to immunomodulator activities as they work synergistically with the immune system to elicit an anti-inflammatory response against damaged tissue or act against external microorganisms, interfering with their growth and activating apoptotic cell death. All of these properties have made microalgae metabolites feasible for use as immunotherapy to treat some of these disorders, as mentioned before [ 28 , 29 , 30 ].…”

Section: Immunomodulatory Activity Of Compounds From Microalgaementioning

confidence: 99%

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Microalgae Bioactive Compounds to Topical Applications Products—A Review

et al. 2022

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Microalgae are complex photosynthetic organisms found in marine and freshwater environments that produce valuable metabolites. Microalgae-derived metabolites have gained remarkable attention in different industrial biotechnological processes and pharmaceutical and cosmetic industries due to their multiple properties, including antioxidant, anti-aging, anti-cancer, phycoimmunomodulatory, anti-inflammatory, and antimicrobial activities. These properties are recognized as promising components for state-of-the-art cosmetics and cosmeceutical formulations. Efforts are being made to develop natural, non-toxic, and environmentally friendly products that replace synthetic products. This review summarizes some potential cosmeceutical applications of microalgae-derived biomolecules, their mechanisms of action, and extraction methods.

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Section: Immunomodulatory Activity Of Compounds From Microalgaementioning

confidence: 99%

Section: Immunomodulatory Activity Of Compounds From Microalgaementioning

confidence: 99%

Section: Immunomodulatory Activity Of Compounds From Microalgaementioning

confidence: 99%

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Microalgae Bioactive Compounds to Topical Applications Products—A Review

et al. 2022

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“…Now a day, the multifunctional immunomodulatory properties of cyanobacteria are gaining much attention in the field of medicine. Cyanobacteria produce various metabolites with different chemical structures, including small molecules of peptides and proteins, polysaccharides, fatty acids, and their derivatives, possessing anti-inflammatory activities [64]. Different cyanobacterial components control the release of certain cytokines from human monocytes and macrophages.…”

Section: Immunomodulatory and Anti-inflammatory Effectsmentioning

confidence: 99%

Potential of Cyanobacteria in Wound Healing

Parwani¹,

Shrivastava²,

Singh³

2022

Cyanobacteria - Recent Advances in Taxonomy and Applications

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The wound care market is rapidly expanding due to the development of innumerable dressings that exhibit specific healing requirements for different wound types. The use of biomaterials as suitable wound dressing material is highly advantageous due to their biocompatibility, biodegradability, and non-toxicity. Cyanobacteria have been widely explored for their potential applications in wound healing, as they are the rich source of bioactive compounds with antibacterial, antitumor, antiviral, antioxidant, and antifungal activities. In recent years this group of organisms has been widely studied due to their immense potential in biomedical applications. Although their different bioactivities can support wound healing in different ways, very few forms have proven utility as a wound-healing agent. This chapter gives an insight into the potential of cyanobacteria in wound healing. Different bioactive compounds present in variable forms of cyanobacteria and their associated activities were reported to support tissue regeneration and wound healing acceleration. As the demand for cost-effective, bioactive wound care products is ever increasing, these organisms have immense potential to be utilized for the development of bioactive wound dressings. Hence, various bioactive compounds of cyanobacteria, their associated activities, and roles in wound healing have been briefly reviewed in this chapter.

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“…This versatility is derived from its ability to synthesize a multiplicity of metabolites distributed among pigments, vitamins, carbohydrates, lipids, and proteins/enzymes. Moreover, several biological properties attributed to microalgae, namely anti-inflammatory [50,51], anti-pyretic [51], and anticancer [52] activities, have shown its potential to high-value compound production.…”

Section: High-value Productsmentioning

confidence: 99%

Microalgae as Sustainable Biofactories to Produce High-Value Lipids: Biodiversity, Exploitation, and Biotechnological Applications

Fernandes

Cordeiro

2021

Marine Drugs

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Microalgae are often called “sustainable biofactories” due to their dual potential to mitigate atmospheric carbon dioxide and produce a great diversity of high-value compounds. Nevertheless, the successful exploitation of microalgae as biofactories for industrial scale is dependent on choosing the right microalga and optimum growth conditions. Due to the rich biodiversity of microalgae, a screening pipeline should be developed to perform microalgal strain selection exploring their growth, robustness, and metabolite production. Current prospects in microalgal biotechnology are turning their focus to high-value lipids for pharmaceutic, nutraceutic, and cosmetic products. Within microalgal lipid fraction, polyunsaturated fatty acids and carotenoids are broadly recognized for their vital functions in human organisms. Microalgal-derived phytosterols are still an underexploited lipid resource despite presenting promising biological activities, including neuroprotective, anti-inflammatory, anti-cancer, neuromodulatory, immunomodulatory, and apoptosis inductive effects. To modulate microalgal biochemical composition, according to the intended field of application, it is important to know the contribution of each cultivation factor, or their combined effects, for the wanted product accumulation. Microalgae have a vital role to play in future low-carbon economy. Since microalgal biodiesel is still costly, it is desirable to explore the potential of oleaginous species for its high-value lipids which present great global market prospects.

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Anti-inflammatory Activity of Bioactive Compounds from Microalgae and Cyanobacteria by Focusing on the Mechanisms of Action

Cited by 47 publications

References 74 publications

Microalgae Bioactive Compounds to Topical Applications Products—A Review

Microalgae Bioactive Compounds to Topical Applications Products—A Review

Potential of Cyanobacteria in Wound Healing

Microalgae as Sustainable Biofactories to Produce High-Value Lipids: Biodiversity, Exploitation, and Biotechnological Applications

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