Anti-inflammatory Action of Green Tea

Ohishi, Tomokazu; Goto, Shingo; Pervin, Monira; Isemura, Mamoru; Nakamura, Yoriyuki

doi:10.2174/1871523015666160915154443

Cited by 215 publications

(148 citation statements)

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“…37 Green tea has anti-inflammatory effects and the production of proinflammatory mediators. 38 We detected no changes in IL-6 and TNF-α levels due to GTE, in contrast to other reports that GTE reduced TNF-α and IL-6 levels. 39 GTE intake increases expression of lipases, reduces adipose fat mass, and in parallel increases inflammatory molecules and cytokines.…”

Section: Discussioncontrasting

confidence: 99%

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Does green tea extract enhance the anti‐inflammatory effects of exercise on fat loss?

Bagheri

Rashidlamir

Ashtary‐Larky

et al. 2020

Brit J Clinical Pharma

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Aims Green tea extract (GTE) can exert antiobesity and anti‐inflammatory effects. Our study determined whether the benefits of GTE are summative with exercise‐induced changes in anthropometric indices, and the levels of inflammatory cytokines, adiponectin and irisin in inactive overweight women. Methods Thirty overweight female participants were randomized to 3 groups: endurance training + placebo (ET + P); endurance training + GTE (ET + GTE); and Control (no exercise) + placebo (Control, n = 10). The exercise intervention consisted of an 8‐week endurance‐training programme of 3 sessions per week (aerobics, aerobic circuit training, and fast walking or jogging at a moderate intensity of 40–59% of the heart rate reserve). The dose of GTE used was 500 mg/day in the form of a green tea capsule. Results Body weight, body mass index, waist to hip ratio and body fat percentage were decreased in both ET + P and ET + GTE interventions (P < .001 for both interventions). The reduction of anthropometric values in the ET + GTE group was significantly higher than ET + P interventions (P < .001). Both exercise interventions also significantly (P < .001) increased adiponectin (ET + GTE = 5.28 mg/mL [95% confidence interval {CI}, 4.48 to 6.08] and ET + P = 3.34 mg/mL [95% CI, 2.76 to 3.92]) and decreased high‐sensitivity C‐reactive protein (hs‐CRP; ET + GTE = −0.95 mg/L [95% CI, −1.15 to −0.75] and ET + P = −0.35 mg/L [95% CI, −0.46 to −0.24]). Changes in adiponectin and hs‐CRP were greater (P < .05) in ET + GTE compared to ET + P. There were no significant differences in irisin, interleukin‐6 or tumour necrosis factor‐α between the 3 groups (P > .05). Conclusions GTE improves exercise‐induced body composition by further decreasing exercise‐induced changes in weight, body mass index, waist to hip ratio and body fat percentage. The combination of GTE and exercise also produced greater changes in anti‐inflammatory (increases in adiponectin) and metabolic (decreases in hs‐CRP) markers than exercise alone.

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Section: Discussioncontrasting

confidence: 99%

“…This modulatory effect of GTE on CRP levels may be a protective mechanism against cardiovascular disease . Green tea has anti‐inflammatory effects and the production of proinflammatory mediators . We detected no changes in IL‐6 and TNF‐α levels due to GTE, in contrast to other reports that GTE reduced TNF‐α and IL‐6 levels .…”

Section: Discussioncontrasting

confidence: 79%

Does green tea extract enhance the anti‐inflammatory effects of exercise on fat loss?

Bagheri

Rashidlamir

Ashtary‐Larky

et al. 2020

Brit J Clinical Pharma

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“…In addition, compared with the full‐differentiated epithelium obtained in 21 days of static culture, In‐OC presents a more pronounced and well‐established crypts‐villus axis, more abundant mucus secretion and a lower TEER value closer to native human intestine. 3D‐HIE obtained in In‐OC was, then, used to perform a biological assay for testing a functional food Epigallocatechin‐3‐gallate (EGCG), an extract of green tea that has been proved to have multiple effects on human pathophysiological processes (Guida et al, ), including anticancer, antioxidant, anti‐inflammatory, anti‐collagenase, and anti‐fibrosis effects (Hsu & Liou, ; Ohishi, Goto, Monira, Isemura, & Nakamura, ; Park et al, ). On this device, we simulated the oral ingestion of a functional food EGCG by loading a epigallocatechin gallate (ECGC) suspension on the apical sealed side.…”

Section: Resultsmentioning

confidence: 99%

Intestine‐on‐chip device increases ECM remodeling inducing faster epithelial cell differentiation

Gregorio

Corrado

Sbrescia

et al. 2019

Biotech & Bioengineering

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An intestine‐on‐chip has been developed to study intestinal physiology and pathophysiology as well as intestinal transport absorption and toxicity studies in a controlled and human similar environment. Here, we report that dynamic culture of an intestine‐on‐chip enhances extracellular matrix (ECM) remodeling of the stroma, basement membrane production and speeds up epithelial differentiation. We developed a three‐dimensional human intestinal stromal equivalent composed of human intestinal subepithelial myofibroblasts embedded in their own ECM. Then, we cultured human colon carcinoma‐derived cells in both static and dynamic conditions in the opportunely designed microfluidic system until the formation of a well‐oriented epithelium. This low cost and handy microfluidic device allows to qualitatively and quantitatively detect epithelial polarization and mucus production as well as monitor barrier function and ECM remodeling after nutraceutical treatment.

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“…• Adequate intake of water, liquids • Green tea with lemon or lime [14] • Irrigation with Surfactin such as Johnson's Baby Shampoo (Isaacs) [15] • Pulsed Irrigation • Mucinex • Pulmazyme • Inhaling warm moist air for nasal mucus…”

Section: Viscosity Therapymentioning

confidence: 99%

Mucociliary Clearance: Measures and Therapies

Grossan¹

2017

Otolaryngol

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Mucociliary Clearance can be measured clinically with the Saccharine Test in the sino-nasal system. When clearance is slow, treat mucus viscosity and slow ciliary beat frequency. Chronic sinusitis and bronchitis are often due to poor MCC. Therapy to upper or lower respiratory system benefits both.Therapy for Mucociliary Clearance includes proteolytic enzymes to reduce mucus viscosity, vibrations for improving ciliary beat frequency, irrigation with Locke-Ringer's solution for cilia frequency, glucosteroids and surfactants.

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Anti-inflammatory Action of Green Tea

Cited by 215 publications

References 0 publications

Does green tea extract enhance the anti‐inflammatory effects of exercise on fat loss?

Does green tea extract enhance the anti‐inflammatory effects of exercise on fat loss?

Intestine‐on‐chip device increases ECM remodeling inducing faster epithelial cell differentiation

Mucociliary Clearance: Measures and Therapies

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