Anti‐hypertensive effect and potential mechanism of gastrodia‐uncaria granules based on network pharmacology and experimental validation
Chu‐Hao Liu,
Qi‐Qi Xue,
Yi‐Qing Zhang
et al.
Abstract:Hypertension has become a major contributor to the morbidity and mortality of cardiovascular diseases worldwide. Despite the evidence of the anti‐hypertensive effect of gastrodia‐uncaria granules (GUG) in hypertensive patients, little is known about its potential therapeutic targets as well as the underlying mechanism. GUG components were sourced from TCMSP and HERB, with bioactive ingredients screened. Hypertension‐related targets were gathered from DisGeNET, OMIM, GeneCards, CTD, and GEO. The STRING database… Show more
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