Anti- hypertensive activity of Ayurvedic medicinal plants

Khanal, Hari; Joshi, Ram Kishor; Upadhyay, Abhishek

doi:10.15406/ijcam.2020.13.00485

Cited by 3 publications

(2 citation statements)

References 15 publications

(11 reference statements)

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“…According to Acharya Charaka, 'Vikshepana' (circulation) of Rasa Dhatu is the karma of Vyan Vayu and Hridaya. [3] Acharya Sushrut has described the circulation process in detail. [4] Chakrapani has mentioned that circulation is a continuous processing in which Rasa, Rakta and other Liquid Dhatus circulate in the body.…”

Section: Nomenclature Given To Htnmentioning

confidence: 99%

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Antihypertensive Drugs - Ayurvedic Perspective

Navdeep Kaur,

Goyal,

Gurpreet Sama

2023

J Ayurveda Integr Med Sci

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Hypertension is a very common disorder, particularly in past middle age. It is not a disease in itself, but is an important risk factor for cardiovascular mortality and morbidity. According to WHO, it is above 140/90 mmHg. An estimated 1.28 billion adults aged 30-79 years worldwide have hypertension. American Association of Heart mentioned that normal blood pressure is less than 120 mmHg systolic and less than 80 mmHg diastolic. Epidemiological studies have confirmed that higher the pressure (systolic or diastolic or both) greater is the risk of cardiovascular disease. The principal focus of Ayurveda is on maintaining good health and adopting a healthy way of life. There is no description of such a single disease which can resemble with hypertension. It can be correlated with Vata Pradhaan Tridoshaj Vyadhi, Raktabhaar, Uchharaktachapa etc and involves dhatus like Rasa and Rakta and gets influenced by Mana. Our ancient science has provided us various drugs which influences the pressure of the blood. These drugs has directly or indirectly role in curing HTN for example Sarpagandha, Jatamansi, Rudraksh, Ashawgandha etc. which should be analysed by the physician clinically. This article would help future researchers and clinicians for administrating these drugs in different forms clinically and help further researches. There are specific alkaloids present in these drugs which influence different centres resulting in decrease in the Blood pressure. The present work deals with enhancing the role of Ayurvedic drugs and promoting more natural ways of treatment.

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Section: Nomenclature Given To Htnmentioning

confidence: 99%

“…Churan-1-2 g [49] Diuretic [48] 18. Sadpushpa has anti-depressant activity which cools the hyperactivity of the mind which releases the constriction in the blood vessels and relaxes the flow of blood.…”

Section: Root Barkmentioning

confidence: 99%

Antihypertensive Drugs - Ayurvedic Perspective

Navdeep Kaur,

Goyal,

Gurpreet Sama

2023

J Ayurveda Integr Med Sci

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Review on Pharmacognostic, Phytochemical and Pharmacological Characteristics of Medicinal Plants which can be used to Design a Novel Ayurvedic Formulation to Treat Hypertension in Multidimensional Approaches

Maurya

Boini

Misro

et al. 2023

CHYR

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Background: Hypertension is a cardiovascular disorder that is an incurable clinical condition. It requires lifelong therapy for its management along with long terms application of synthetic drugs associated with severe toxicity in multiple organs. However, the therapeutic application of herbal medicines to treat hypertension has gained considerable attention. The limitations and hurdles associated with conventional plant extract medications are their safety, efficacy, dose, and unknown biological activity. Objective: In the modern era, the active phytoconstituent-based formulation has come into trend. Various extraction techniques have been reported to extract and isolate active phytoconstituents. Pharmacognostic, physiochemical, phytochemical, and quantitative analytical methods were developed for their qualitative and quantitative analysis. The passage of time and changes in lifestyle also modulate the variable cause of hypertension. Single-drug-based approach therapy cannot efficiently control the cause of hypertension. Designing a potent herbal formulation with different active constituents and modes of action against hypertension is necessary to effectively manage hypertension. Method: This review comprises a selection of three different plants, Boerhavia diffusa, Rauwolfia Serpentina, and Elaeocarpus ganitrus exhibiting antihypertension activity. Result: The objective behind selecting individual plants is their active constituents which have different mechanisms of action for the treatment of hypertension. This review comprises the various extraction methods of the active phytoconstituents and pharmacognostic, physiochemical, phytochemical, and quantitative analysis parameters, respectively. It also lists active phytoconstituents present in plants and the different pharmacological modes of action. Selected plant extracts have different antihypertensive mechanisms. Extract of Boerhavia diffusa consisting of Liriodendron & Syringaresnol mono β-D-Glucosidase exhibit Ca2+ channel antagonistic activity; where Reserpine is a phytoconstituent of Rauwolfia serpentina, which depletes catecholamine, Ajmalin shows an antiarrhythmic effect by blocking the sodium channel and the aqueous extract of E. ganitrus seeds reduces mean arterial blood pressure by inhibiting the ACE enzyme. Conclusion: It has been revealed that poly-herbal formulation of respective phytoconstituent can be used as potent antihypertensive medicine to treat hypertension effectively.

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Medicinal Plants as Calcium-Channel Blockers against Hypertension

Joshi¹,

Shelke²

2021

IJPSRR

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Anti- hypertensive activity of Ayurvedic medicinal plants

Cited by 3 publications

References 15 publications

Antihypertensive Drugs - Ayurvedic Perspective

Antihypertensive Drugs - Ayurvedic Perspective

Review on Pharmacognostic, Phytochemical and Pharmacological Characteristics of Medicinal Plants which can be used to Design a Novel Ayurvedic Formulation to Treat Hypertension in Multidimensional Approaches

Medicinal Plants as Calcium-Channel Blockers against Hypertension

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