Anti Hyperglycemic Activity of Elytraria Acaulis Lind. on Streptozotocin-Induced Diabetic Rats

Koshy, Ruby K; B, Raj Kapoor; Azamthulla, Mohammad

doi:10.4172/2167-0412.1000103

Cited by 6 publications

(2 citation statements)

References 22 publications

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“…Diabetes mellitus is a growing public health problem both in developing and developed nations, and a major cause of morbidity in the world [14,15], thus research efforts on it are justified. The most frequently documented risk factors associated with type 2 diabetes include older age, obesity, family history of the disease, hypertension, dyslipidemia, physical inactivity, and belonging to certain racial/ethnic groups [16].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Diabetes Mellitus in Bukuru Metropolis of Plateau State

Oluchukwu¹

2013

IOSR-JPBS

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This study aimed to determine the prevalence of diabetes mellitus (DM) and its associated risk factors in Bukuru Metropolis in jos south L.G.A of Plateau state. Personal and demographic data were obtained through the use of questionnaire. Blood samples were collected from participants after an overnight fast. Weight, height, and blood pressure (BP) measurements were taken. Results were analysed statistically by t-test, Chy square test, and analysis of variance. A total of 998 individuals aged 25-70 years comprising of 487(48.8%) men and 511(51.2%) women were recruited for the study. Subjects were classified into diabetic and control groups based on the laboratory findings. DM was defined according to 1999 WHO criteria. Individuals who were previously known to have diabetes based on history and laboratory data were classified as having diabetes without oral glucose tolerance test (OGTT). Thirty-six subjects were found to be diabetic for a prevalence of 3.6%, made up of 2.2% previously known cases and 1.4% newly diagnosed, majority being asymptomatic. The prevalence rates were 1.9% and 1.7% for males and females respectively. There was no significance difference (p>0.05) in the prevalence between the sexes. Body mass index (BMI) ≥25 kg/ m 2 , BP >140/90 mm Hg, family history of diabetes, physical inactivity and older age were associated with significantly (p<0.05) higher prevalence of type 2 diabetes. The asymptomatic nature of diabetes recorded in this study points to the need to improve health services and awareness in the general population.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Diabetes Mellitus in Bukuru Metropolis of Plateau State

Oluchukwu¹

2013

IOSR-JPBS

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“…Diabetes mellitus is a serious health problem with high rates of incidence and mortality all over the world (1). Globally as of 2010 it was estimated that there were 285 million people with diabetes, type 2 making up about 90-95% of all diagnosed cases (2).…”

Section: Introductionmentioning

confidence: 99%

Studies on the Effect of Diet and Drug Therapies on Serum Ferritin, a Predictor of Type 2 Diabetes Mellitus

Okonkwo¹

2013

iosrphr

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Background and Objective: Epidemiological studies have established a link between serum ferritin concentration and type 2 diabetes. This work was carried out to ascertain the effect of therapeutic regimen on the earlier established links. Materials and Methods: Two hundred subjects comprising 130 type 2 diabetics and 70 apparently healthy controls were involved in the survey. Anthropometric parameters, fasting plasma glucose (FPG), Serum levels of ferritin, lipids and biochemical indicators of complications of type 2 DM were determined. Results were analysed statistically by ANOVA, and Pearson correlation. Results: Serum ferritin, showed a positive correlation with FPG, BP, TC, triglyceride, and TC/HDL ratio among diabetic subjects. With subjects classified based on the antidiabetic therapy, the mean serum ferritin level of the subjects on a combination therapy of drug and diet was significantly (p<0.05) lower than the level in those on either drug or diet alone. Serum ferritin level showed a positive correlation with TC and TC/HDL ratio, in diabetics on drug alone and with PFG, TC, and TG levels in subjects on diet alone but with none in subjects on a combined therapy. Conclusion: This finding suggests the need to take into due consideration type of diabetic medication when interpreting relationship between iron stores and diabetic risk.

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