Anti‐hepatitis C virus seroconversion in blood donors in Japan

The Official Requirements for Platelet Concentrates

“…Quality control of PC is an area of continuing interest [4]. There are a myriad of assays available including platelet swirl, morphology score, aggregation, granule release, cytosolic enzyme discharge, osmotic stress, metabolic, and many others [4].…”

“…There are a myriad of assays available including platelet swirl, morphology score, aggregation, granule release, cytosolic enzyme discharge, osmotic stress, metabolic, and many others [4]. In my opinion, no assay is a better predictor of in vivo platelet recovery and survival than is the simple measurement of pH.…”

“…In the setting of massive transfusion during orthotopic liver transplantation, we routinely provide 10 units to adult recipients [4]. For adult patients with splenomegaly who are bleeding and need therapeutic doses of platelets, we also provide 10 units.…”

“…from a total of 12,000 donors) were thus systematically checked for bacterial contamination: no real contamination was found (16/6,489 false-positive results) [4].…”

“…However, a recent UK regulation is that all cellular components for neonates must be leucocyte depleted. An additional specification is being developed for a hyperconcentrated platelet component for intrauterine use [4].…”