Anti-Helicobacter activity of medicinal plants and probiotics as alternatives for Helicobacter pylori treatment: Review article

Abstract

<jats:p>Helicobacter pylori, a gram-negative bacterium, known factor for chronic active gastritis, stomach and peptic ulceration, which may progress to gastric cancer. It is also associated with other non-gastric diseases such as stroke, diabetes mellitus and alzheimer’s disease. Although conventional treatment achieved a great advancements in controlling H.pylori infection nowadays it is not effective thus it’s intended to find some other alternative sources that may be used alone or in combination with antibiotics to eradicate the infection. Recently published literature of natural sources such as plant -derived bioactive compounds and probiotics are studied for their reduced side effects and for being safe and inexpensive. However, the mechanism of action by which these herbs and probiotics exert their medicinal properties in H.pylori treatment is still not fully clear. In this review, we highlight the potential antibacterial mechanisms of some traditionally used bioactive compounds and their possible role on H.pylori colonization. On the other hand, we focused on the possible inhibitory role of probiotics in the eradication of H. pylori infection through the release of organic acids and their role in the stabilization of the gastric barrier function in order to decrease the mucosal inflammation, modulate H.pylori colonization and enhance compliance in infected patients.</jats:p>

The Use of Medicinal Herbs to Treat Male Infertility in Jordan: Evidence-Based Review

“…For many years botanical medicine was being used to treat different diseases because they are cheap, available, and with tolerated side effects [7]. As a treatment for infertility, botanical medicine is used to get a healthy ovum and enhance spermatozoa production or to increase libido [8].…”

In Silico and In Vitro Investigation of Anti Helicobacter Activity of Selected Phytochemicals

“…[ 4 ] Although the mode of transmission of H. pylori is not fully understood yet, but it seems that oral–oral, gastro–oral, and fecal–oral routes are possible routes for transmission while they are directly influenced by the level of hygiene and the socio-economic status of the country. [ 5 ]…”