Anti-diabetic Potential of some Spices Commonly used in Diet with other Pharmacological Activities: A Review

Abstract

Background:: Diabetes mellitus is a chronic metabolic disorder, the prevalence of which is rising alarmingly throughout the world and imposes a serious impact on the health of population as well as national economies. Effective management and primary prevention are essential to decrease the burden of diabetes faced by all nations. Although different therapies are available for diabetes, no known therapy can completely cure the disease and many of them have a number of side effects with other limitations like long term treatment, expensiveness and less availability. Hence, the present review has given an emphasis on common dietary materials to find out a readily available source of antidiabetic agents. Objective: The purpose of this work is to explore the antidiabetic properties of certain spices most frequently used in Bangladeshi kitchen and reported for the use in traditional treatment of diabetes and/or investigated scientifically for antidiabetic activity. Methods: Two electronic databases namely Pub Med and Google Scholar were used for conducting comprehensive search to collect information and data. Results: In this review, a total of 10 spices have been compiled with brief description about their origin, part used, chemical constituents, mechanism of action, methods of experiment, model animals and reported beneficial effects in diabetes with other pharmacological activities. Conclusion: The observed results of this study indicate the possibility of developing a therapeutic strategy called alternative and complementary medicine for the management of diabetes. The results also provide a starting point for researchers working with bioactive dietary plants that have antidiabetic potential.

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“…It belongs to the family Opiliaceae. While it has been used traditionally in some African cultures for medicinal purposes, scientific research on its bioactivity and pharmacological properties is limited 8 . Here are some potential bioactive and pharmacological activities associated with Opilia celtidifolia.…”