Anti-diabetic and Anti-oxidative Effects of Opuntia humifusa Cladodes

Lee, Jina; Kim, Hyeong-Eun; Kim, Yong-Suk

doi:10.3746/jkfn.2014.43.5.661

Cited by 19 publications

(4 citation statements)

References 22 publications

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“…Vários compostos extraídos dos cladódios apresentam ação farmacológica destacando-se a atividade emoliente, gastroprotetora, antioxidante, anti-inflamatória, neuroprotetora e hipocolesterolêmica (ESKICIOGLU; KAMILOGLU; NILUFER-ERDIL, 2015;GALATI et al, 2007;LEE;KIM;KIM, 2014;TROMBETTA et al, 2006). Devido aos problemas agrícolas ligados ao aumento das zonas áridas e a escassez dos recursos hídricos, algumas cactáceas estão ganhando importância como fonte de alimento eficaz à população humana (STINTZING;CARLE, 2005).…”

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CARACTERÍSTICAS FÍSICAS, QUÍMICAS E BROMATOLÓGICAS DE PALMA GIGANTE (Opuntia ficus-indica) E MIÚDA (Nopalea cochenillifera) ORIUNDAS DO ESTADO DA PARAÍBA

Silva

Souza²,

Ribeiro³

et al. 2015

RBTA

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Resumo A palma é originária do México e pertencente à família das cactáceas. É cultivada em muitos países e adapta-se bem aos climas áridos, semiáridos e nos IntroduçãoO Brasil é o país que apresenta a maior diversidade genética vegetal do mundo, com cerca de 55.000 espécies catalogadas e que se destaca pela riqueza em espécies com potencial para uso na agricultura, melhoramento genético e domesticação de frutíferas. O aproveitamento da variabilidade

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CARACTERÍSTICAS FÍSICAS, QUÍMICAS E BROMATOLÓGICAS DE PALMA GIGANTE (Opuntia ficus-indica) E MIÚDA (Nopalea cochenillifera) ORIUNDAS DO ESTADO DA PARAÍBA

Silva

Souza²,

Ribeiro³

et al. 2015

RBTA

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“…Human studies showed that consumption of OFI cladodes at dietary-achievable amounts was associated with a remarkable reduction of oxidative stress in healthy subjects (Tesoriere et al , 2004). Lee et al (2014) investigated the antioxidant activity of cactus nopalitos and concluded that this antioxidant property was due to several compounds, particularly flavonoids and vitamins. Our results are in accordance with published studies in rats with diabete type 2, which underlined the relevant preventive potential of OFI cladodes (Ncibi et al , 2008: Zourgui et al , 2008; Harrat et al , 2019).…”

Section: Discussionmentioning

confidence: 99%

The cactus cladode (Opuntia ficus indica) modulates uricemia, improves endothelial dysfunction and corrects oxidative damage in rats fed a cafeteria diet

Chekkal

Harrat

Bensalah

et al. 2020

WJSTSD

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PurposeThe effects of Opuntia ficus indica (OFI) cladodes on uricemia level, endothelial dysfunction and oxidative damage were studied in young rats fed a cafeteria diet (CD).Design/methodology/approachA total of 16 young male Wistar rats (weighing 110 ± 20 g and four weeks old) were divided into two homogenous groups. The first group received a CD containing 50% of hyperlipidic diet and 50% of junk food mix (processed mix: hyper-fat, hyper-salted and sweetened) (CD group), and the second group (CD + OFI nopalitos) received the same diet supplemented with 50 g of fresh OFI nopalitos (young cladodes) for 30 days.FindingsOFI nopalitos regulate the hyperuricemia, improve the endothelial dysfunction by raising the bioavailability of nitric oxide(NO) and reduce prooxidant markers by reducing lipid peroxidation and protein oxidation (p < 0.05) and boosting antioxidant capacity and enhancing the antioxidant enzymes activities (p < 0.05) in blood and aorta tissues of rats early fed with a high-fat diet /junk food.Social implicationsBy-products of OFI have specific functional properties that may be beneficial in metabolic disorders and offer a better alternative with an economic and sustainable development perspective.Originality/valueBy-products of OFI highlight potential functional properties mainly based on its potent antioxidant capacity. By-products of OFI can be used as a promising nutraceutical resource to prevent various metabolic disorders in relation with cardiovascular diseases or hyperuricemia in subjects consuming junk food and or living in the Western society to reach the objectives of health policy and maintain a sustainable health system development.

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“…Although studies have examined effects of Opuntia extracts on the lipid metabolism of diabetic mice (10) and potential use as an antidiabetic and antioxidant agent (11), few studies have examined whether treatment with O. humifusa can improve atopic dermatitis. Herein, extracts of O. humifusa cladodes were examined for protective effects against atopic dermatitis in NC/Nga mice with the ultimate aim of use as a functional material.…”

Section: Introductionmentioning

confidence: 99%

Protective effects of Opuntia humifusa cladode extracts against biostir AD-induced atopic dermatitis in NC/Nga mice

Lee

Kim

2015

Food Sci Biotechnol

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The abilities of water and ethanol extracts of Opuntia humifusa cladode powder to protect against atopic dermatitis in NC/Nga mice were investigated for application of O. humifusa cladodes as functional food materials. Water extract-treated group (OHW) and ethanol extracttreated group (OHE) mice exhibited protective effects against skin lesions, such as reduced hemorrhaging and epidermolysis. The number of mast cells in skin tissues of OHE group mice was 9.3±2.7 units, which was significantly (p<0.05) decreased compared with other group mice. The serum level of IgE in OHE group mice (1,156±35.19 ng/ mL) was significantly (p<0.05) decreased, compared with other group mice. The serum histamine concentrations in OHW and OHE groups mice were significantly (p<0.05) decreased, compared with control group mice. Overall, 75% ethanol extracts provided greater protection than water extracts. O. humifusa cladode extracts have potential for future use as functional materials.

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Anti-diabetic and Anti-oxidative Effects of Opuntia humifusa Cladodes

Cited by 19 publications

References 22 publications

CARACTERÍSTICAS FÍSICAS, QUÍMICAS E BROMATOLÓGICAS DE PALMA GIGANTE (Opuntia ficus-indica) E MIÚDA (Nopalea cochenillifera) ORIUNDAS DO ESTADO DA PARAÍBA

CARACTERÍSTICAS FÍSICAS, QUÍMICAS E BROMATOLÓGICAS DE PALMA GIGANTE (Opuntia ficus-indica) E MIÚDA (Nopalea cochenillifera) ORIUNDAS DO ESTADO DA PARAÍBA

The cactus cladode (Opuntia ficus indica) modulates uricemia, improves endothelial dysfunction and corrects oxidative damage in rats fed a cafeteria diet

Protective effects of Opuntia humifusa cladode extracts against biostir AD-induced atopic dermatitis in NC/Nga mice

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