2016
DOI: 10.24953/turkjped.2016.04.008
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Anti-cyclic citrullinated peptide antibodies are not frequently observed in children with type 1 diabetes mellitus: a single-center study

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“…Katherine P and al suggest that part of this association could be attributed to the presence or effect of the 620W PTPN22 allele, which corroborates with previous studies demonstrating that the PTPN22 polymorphism is a risk factor for T1D as well as for anti-CCP positive RA [3,19,20]. However, other authors [21,22] reported the rarity of anti-CCP antibody positivity among adult patients with T1D. When the myocardial infarction occurred, our patient had a high cardiovascular risk as her diabetes duration is more than 10 years but without any cardiovascular risk factors and with well replaced peripheral hypothyroidism, this prompted us to search another aetiology.…”
Section: Discussionsupporting
confidence: 64%
“…Katherine P and al suggest that part of this association could be attributed to the presence or effect of the 620W PTPN22 allele, which corroborates with previous studies demonstrating that the PTPN22 polymorphism is a risk factor for T1D as well as for anti-CCP positive RA [3,19,20]. However, other authors [21,22] reported the rarity of anti-CCP antibody positivity among adult patients with T1D. When the myocardial infarction occurred, our patient had a high cardiovascular risk as her diabetes duration is more than 10 years but without any cardiovascular risk factors and with well replaced peripheral hypothyroidism, this prompted us to search another aetiology.…”
Section: Discussionsupporting
confidence: 64%