Abstract:Introduction: Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular injury, autoimmunity and tissue fibrosis. Usually collagen type V (V Col) is found hidden between the heterotypical fibers. It was discovered in the rheumatology department at the University of São Paulo (FMUSP) that deposition of this collagen occurs, however with anomalous morphology in SSc patient's tissue, suggesting that V Col is an important molecule in fibrosis and autoimmunity process. The V Col molecule, which ha… Show more
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