2023
DOI: 10.1099/jmm.0.001691
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Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development

Abstract: Introduction. Azelastine hydrochloride, a second-generation histamine H1 receptor (H1R) antagonist, exhibits anti-chlamydial effects against Chlamydia trachomatis (CT) in HeLa cells (genital infection model). Hypothesis/Gap Statement. Non-antibiotic pharmaceutical interactions with CT are an understudied field and the anti-chlamydial effects of azelastine are a potential interaction requiri… Show more

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