Anti-cell adhesion characteristics of nanotextured surface for implantable biomedical device

Han, Eui Don; Kim, Byeong Hee; Seo, Young Ho

doi:10.1007/s12541-017-0031-6

Cited by 10 publications

(6 citation statements)

References 28 publications

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“…The cytotoxicity of Ormocers has been extensively tested and they have long been used in dentistry as restoration materials [5][6][7][8]. While most biocompatibility tests involving Ormocomp® were in vitro, preliminary in vivo tests of Ormocore®, another variant in the Ormocer family, have shown good biocompatibility [21,22].…”

Section: Discussionmentioning

confidence: 99%

“…The properties of Ormocers can be tuned with the addition of other copolymers and photoinitiators [4]. The cytotoxicity of Ormocers has been extensively tested and they have been used in dentistry since 1988 [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

“…In this study Ormocomp® was chosen as it is readily available and extensively used in the fabrication of various microdevices such as microfluidic devices [9][10][11] and cell growth scaffolds [6,7]. The optical transparency of Ormocomp® allows for the fabrication of optical waveguides and sensors [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

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Body-Implantable RFID Tags Based on Ormocer Printed Circuit Board Technology

et al. 2020

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This paper demonstrates, for the first time, a biocompatible RFID tag fabricated on an Ormocer substrate, and encapsulated in it. Ormocomp belongs to a group of hybrid organic-inorganic photostructurable materials called Ormocers. It is biocompatible, chemically inert, and electrically insulating-ideal for body-implantable applications. In this study we developed an Ormocomp-based printed circuit board (PCB) and packaging method, and implemented a biocompatible RFID tag. Index Terms-Implantable RFID tag, Ormocer, biocompatible, printed circuit board, packaging I.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Body-Implantable RFID Tags Based on Ormocer Printed Circuit Board Technology

et al. 2020

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“…The microtopology designed on the surface of the implant can effectively reduce the adhesion of macrophages and fibroblasts, thus avoiding the inflammatory reaction when placed the implant into the human body [155]. Han et al [156] studied the anti-cell adhesion properties of several different micro topologies. It was found that surface nanotexture technology improved the anti-cell viscosity of the implant surface and provided a new design for the surface modification of implants.…”

Section: Surface Modificationmentioning

confidence: 99%

Additive Manufacturing of Customized Metallic Orthopedic Implants: Materials, Structures, and Surface Modifications

Bai

Cheng

Chen

et al. 2019

Metals

121

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Metals have been used for orthopedic implants for a long time due to their excellent mechanical properties. With the rapid development of additive manufacturing (AM) technology, studying customized implants with complex microstructures for patients has become a trend of various bone defect repair. A superior customized implant should have good biocompatibility and mechanical properties matching the defect bone. To meet the performance requirements of implants, this paper introduces the biomedical metallic materials currently applied to orthopedic implants from the design to manufacture, elaborates the structure design and surface modification of the orthopedic implant. By selecting the appropriate implant material and processing method, optimizing the implant structure and modifying the surface can ensure the performance requirements of the implant. Finally, this paper discusses the future development trend of the orthopedic implant.

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“…It is well known that not only materials, but also certain micro-and nanostructured surfaces, can influence the adhesion, orientation and growth of cells on surfaces (e.g., [11][12][13][14]); in particular, structures in the same size region as the cells could cause a guidance of the cells. It has been shown that line and space structures could assist in aligning cells (e.g., [15]).…”

Section: Introductionmentioning

confidence: 99%

Nanoimprinted Hierarchical Micro-/Nanostructured Substrates for the Growth of Cardiomyocyte Fibers

Mühlberger,

Kopp,

Deyett

et al. 2023

Nanomanufacturing

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Investigating the behavior of cardiomyocytes is an important part of drug development. We present a structure and a related nanoimprint-based fabrication method, where the cardiomyocytes form isolated fibers, which is beneficial for drug testing, more closely representing the structure of the cardiomyocytes in vivo. We found that channel structures with walls with a rough top surface stimulate cardiomyocytes to form such fibers, as desired. Nanoimprint lithography is used as a fast and cost-efficient method to fabricate our hierarchically structured cell growth substrates.

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Anti-cell adhesion characteristics of nanotextured surface for implantable biomedical device

Cited by 10 publications

References 28 publications

Body-Implantable RFID Tags Based on Ormocer Printed Circuit Board Technology

Body-Implantable RFID Tags Based on Ormocer Printed Circuit Board Technology

Additive Manufacturing of Customized Metallic Orthopedic Implants: Materials, Structures, and Surface Modifications

Nanoimprinted Hierarchical Micro-/Nanostructured Substrates for the Growth of Cardiomyocyte Fibers

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