Anti‐bacterial effects of functional cosmetics containing silver ions (Ag⁺) on problematic toenails in Republic of Korea

Abstract

Background: Problematic toenails caused by various diseases that are infected by various bacteria are discolored or deformed if left unattended for a long time are gradually increasing in modern society. Accordingly, the present study examines the anti-bacterial effects of LCN products, focused on Pseudomonas aeruginosa and Trichophyton rubrum, which can appear in problematic toenail symptoms. After the treatment, a significant anti-bacterial effect occurring on problematic toenails when a product containing silver ion (Ag + ) will be analyzed. Methods:The anti-bacterial activity of LCN functional gel products in anti-fungal and/or anti-bacterial potency was confirmed by the paper disk method against two strains (Pseudomonas aeruginosa and Trichophyton rubum).Results: From July 2019 to October 2019, 30 men and women in their 20s and 50s who needed to manage problematic toenails in Wonju city, Gangwon-do, Republic of Korea, were asked to use LCN products once every two weeks. After 4 months, changes in the managed toenails were observed. Both products showed very good anti-microbial activity against, Trichophyton rubum but a very weak one against Pseudomonas aeruginosa. Conclusion:As a result of this study, although there was a difference between individuals, the feet treated with LCN products showed effective anti-bacterial activity against topical anti-bacterial effects.

Lipopeptide C17 Fengycin B Exhibits a Novel Antifungal Mechanism by Triggering Metacaspase-Dependent Apoptosis in Fusarium oxysporum

“…Antifungal Activity Assay. The antifungal activity of purified fengycin was tested by the disk diffusion method described by Lee et al 16 One milliliter of FJAT-31362 suspension at a concentration of 10 5 conidia/mL was added to 100 mL of PDA semisolid medium at 50 °C and poured onto PDA solid medium. Six millimeter sterilized paper disks were soaked in 2 mg/mL purified fengycin for 1 h and then placed onto the PDA solid media as above.…”