Anti-Atherosclerotic Role of Olive Oil in Rats

Abstract

The increase in dietary cholesterol to perform a rat model for atherosclerotic diet would result in a significant increase in serum levels of total cholesterol and malondialdehyde and blood SOD activity in rats. Moreover, there was significant decrease in serum levels of LDL-C, triacylglycerol and GSH, In addition to blood catalase activity. Although, there was a nonsignificant change in in serum HDL-C and blood GPx activity. However, dietary supplementation with olive oil mixed with atherosclerotic diet ameliorates this undesirable effect. water was offered ad libitum according to National Research Council (1995).