Anti-angiogenic activity and safety of intraocular application of triterpenes

Toledo, Cibele Rodrigues; Pereira, Vinícius Oliveira de Moura; Duarte, Lucienir Pains; Sousa, Grasiely Faria de; Silva-Cunha, Armando

doi:10.1007/s10633-021-09841-z

Cited by 5 publications

(1 citation statement)

References 32 publications

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“…The compound 3ꞵ-friedelinol is a major constituent of Euphorbia vajravelui where it reported no toxic effect on human cardiac cell line and no cytotoxic towards a cervical cancer cell line [27]. The non-toxic effects of this compound were also observed when evaluated using ARPE-19 or human retinal pigmented epithelium cell line and CRL2120 or human skin fibroblast [28,29]. Squalene is a triterpene hydrocarbon that is ubiquitously found in nature.…”

Section: Phytochemistrymentioning

confidence: 99%

Artocarpus Camansi Blanco: A Review on Its Traditional Use, Nutritional Value, Phytochemistry, and Pharmacology

Bicaldo¹

2022

Preprint

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Artocarpus camansi Blanco or breadnut (Family: Moraceae) is primarily found in tropical regions of the world. Different parts of the plant provide potential use in medicine, nutraceutical development, and livelihood. The present review attempts to document literature on the traditional use, nutritional value, phytochemistry, and pharmacological investigation carried out with breadnuts. The included literatures of the plant were collected from various sources and databases like Google scholar, PubMed, ScienceDirect, Crossref, and Scopus. Breadnuts are rich in secondary metabolites. Studies have reported the isolation of several triterpenoid compounds and the broad spectrum of its pharmacological activities such as antidiabetic, antimalarial, antioxidant, anti-tumor, antibacterial, and immunomodulatory properties. The approximate composition of the seed and the fruit also highlights the nutritional importance of this plant. A. camansi Blanco is an underutilized tree that holds significant potential if further research and sustainable conservation is applied. Efforts to mainstream its use as functional food and increase awareness among the locals should also be given attention.

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Section: Phytochemistrymentioning

confidence: 99%