Anti-angiogenesis efficacy of the aqueous extract of Allium sativum and its combination with melatonin in an animal model: in vivo and ex vivo studies
Khalid Ali Obaid
Abstract:To better understand Allium sativum’s anti-angiogenesis activity, we undertook this study to examine its effect on the ex vivo rat aortic ring and the in vivo chick chorioallantoic membrane. Additionally, we compare Allium sativum’s anti-angiogenesis activity to melatonin and study the benefits of their combination. The study included six albino male rats (aged 5–7 weeks). The rats were euthanized, and then the thoracic aorta was removed and cut into rings that were 1 mm thick. The study was divided into three… Show more
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